The Preparation of α-Trifluoro-<i>p</i>-phenylacetophenone

Saunders, J. H.; Slocombe, R. J.; Hardy, Edgar E.

doi:10.1021/ja01170a519

Cited by 13 publications

(7 citation statements)

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“…However, he prepared the diazide by treating substituted succinic hydrazides with nitrous acid. Yields from the reaction are usually good, as in the case of undecyl isocyanate, which was obtained in [81][82][83][84][85][86] per cent yield (2). A complete survey of such preparations reported in the literature is given by Smith (96).…”

Section: Rcons Rcon Rncomentioning

confidence: 99%

The Chemistry of the Organic Isocyanates.

Saunders¹,

Slocombe²

1948

Chem. Rev.

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182

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Section: Rcons Rcon Rncomentioning

confidence: 99%

The Chemistry of the Organic Isocyanates.

Saunders¹,

Slocombe²

1948

Chem. Rev.

Self Cite

182

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“…2 shows that extracts of L. casei and B. subtilis gave single peaks, which possessed both activities, while the E. coli extract yielded two distinctly separated peaks, one of which was active mainly with uridine and the other mainly with thymidine. These resuits suggested that the L. casei extract contains a single pyrimidine nucleoside phosphorylase, as was reported for B. stearothermophilus, H. influenzae and B. subtilis [10,11]. However, this assumption was disproved by the results of the purification experiments.…”

Section: Sucrose Density Gradient Centrifugation Studiesmentioning

confidence: 72%

“…The uridine phosphorylase of E.coli K12 also shows some activity with deoxyuridine and thymidine [7]. It was reported that Bacillus stearothermophilus, Haemophilus influenzae and possibly B. subtilis, contain one enzyme, pyrimidine nucleoside phosphorylase, (EC 2.4.2.2) [10,11], which acts with both thymidine and uridine.…”

Section: Introductionmentioning

confidence: 99%

Thymidine phosphorylase and uridine phosphorylase of Lactobacillus casei

Avraham

Yashphe

Grossowicz

1988

FEMS Microbiology Letters

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SUMMARYCrude extracts of Lactobacillus casei, were found to possess both thymidine phosphorylase and uridine phosphorylase activities, which were associated with a single sucrose gradient band. However, using dye ligand chromatography (Green A), two enzymatic fractions were obtained each of which possessed mainly one of these activities. By this procedure, the uridine phosphorylase was purified 329-fold and the thymidine phosphorylase about 25-fold. The existence of the two phosphorylases was supported by Kin, K~, pH optimum, and heat stability studies. Identical bands were obtained on sucrose gradient sedimentation for the purified enzymes and for their mixture in a crude extract, suggesting that they have similar sedimentation coefficients, and do not form an aggregate in the crude extract.

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“…15 Thus, 6 ml (49 mmol) of perfluorobutanoic acid, CF 3 CF 2 CF 2 C(O)OH, was slowly added using a dropping funnel attached to a twin-neck round bottom flask containing 12.50 g (60 mmol) of PCl 5 . Two "U" shaped traps immersed in cool baths (-50 °C and -80 °C, respectively) were connected to the condenser and a CaCl 2 trap was 6 microwave spectroscopy.…”

Section: Synthesismentioning

confidence: 99%

“…The title compound was synthesized by reaction of perfluorobutanoic acid with phosphorus pentachloride according to the usual method . Thus, 6 mL (49 mmol) of perfluorobutanoic acid, CF 3 CF 2 CF 2 C(O)OH, was slowly added using a dropping funnel attached to a twin-neck round-bottom flask containing 12.50 g (60 mmol) of PCl 5 .…”

Section: Experimental Sectionmentioning

confidence: 99%

Photoexcitation, Photoionization, and Photofragmentantion of CF₃CF₂CF₂C(O)Cl Using Synchrotron Radiation between 13 and 720 eV

et al. 2015

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The main inner shell ionization edges of gaseous CF3CF2CF2C(O)Cl, including Cl 2p, C 1s, O 1s, and F 1s, have been measured in Total Ion Yield (TIY) mode by using tunable synchrotron radiation, and several resonance transitions have been assigned with the help of quantum chemical calculations. Interestingly, resonance transitions observed in the C 1s region can be assigned to different carbon atoms in the molecule according to the degree of fluorine substitution. Ionic photofragmentation processes have been studied by time-of-flight mass spectrometry in the Photoelectron-Photoion-Coincidence (PEPICO) and Photoelectron-Photoion-Photoion-Coincidence (PEPIPICO) modes. These techniques revealed a "memory-lost" effect especially around the C 1s region, since the fragmentation events are independent of the energy range considered. Moreover, different fragmentation mechanisms were inferred from these spectra in the valence (13.0-21.0 eV) as well as in the inner (180.0-750.0 eV) electronic energy regions. The vibrational spectral features of CF3CF2CF2C(O)Cl have been interpreted in terms of a conformational equilibrium between two conformations (gauche and anti of the CC single bond with respect to the CCl one) at room temperature, as determined from quantum chemical calculations and the detailed analysis of the infrared spectrum.

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The Preparation of α-Trifluoro-p-phenylacetophenone

Cited by 13 publications

References 0 publications

The Chemistry of the Organic Isocyanates.

The Chemistry of the Organic Isocyanates.

Thymidine phosphorylase and uridine phosphorylase of Lactobacillus casei

Photoexcitation, Photoionization, and Photofragmentantion of CF₃CF₂CF₂C(O)Cl Using Synchrotron Radiation between 13 and 720 eV

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The Preparation of α-Trifluoro-p-phenylacetophenone

Cited by 13 publications

References 0 publications

The Chemistry of the Organic Isocyanates.

The Chemistry of the Organic Isocyanates.

Thymidine phosphorylase and uridine phosphorylase of Lactobacillus casei

Photoexcitation, Photoionization, and Photofragmentantion of CF3CF2CF2C(O)Cl Using Synchrotron Radiation between 13 and 720 eV

Contact Info

Product

Resources

About

Photoexcitation, Photoionization, and Photofragmentantion of CF₃CF₂CF₂C(O)Cl Using Synchrotron Radiation between 13 and 720 eV