The preparation of propargyltrimethylsilanes

Synthesis of propargyl silanes from terminal alkynesviaa migratory Sonogashira reaction

“…In contrast, the direct conversion of widely available terminal alkynes to propargyl silanes is a conceptually simple and attractive approach (Scheme 1B, eqn (6)). [15][16][17][18] This strategy is usually performed by deprotonation of terminal alkynes and then a reaction with a silylmethyl electrophile, such as trimethylsilylmethyl iodide.…”