The preparation of fluorine-18 with an electron linear accelerator for applications in medical and biological investigations

Study of the possibility of the production and separation of the 18F radioisotope at electron accelerators

“…Following [13], we used ion exchange chromatog raphy utilizing Dowex 50 × 8 cation exchange resin (100-200 mesh) produced by Fluka Analytical in order to separate sodium from fluorine. The adsorbent was initially in Na + form and had to be exposed to 4M HCl for an hour in order to convert it into H + form.…”

“…The production of radioisotopes at electron accel erators has been repeatedly proposed as a potential alternative to the production at nuclear reactors and accelerators of heavy charged particles (see, for exam ple, [12][13][14][15], where the production of 18 F at electron accelerators is studied). The increasing demand for medical radioisotopes necessitates the intensification of studies of the prospects of radioisotope production at electron accelerators.…”