“…2-Pyridinylboronic acids and esters using halogen-metal exchange (HMe) are generally synthesized from 2-bromopyridines (3, X = 2-Br). 5,6,13,17,[34][35][36][37][38][39][40][41][42] In the particular case of compound 3 (X = 2-I), 2-iodopyridine was used. 16 To improve the stability (particularly in air and water), pyridine-2-boronates such as 6, 34 7, 35,36 and 8 37,38 were developed.…”