The predominance of surface over deep cardiac injury in producing changes in the electrocardiogram

Kisch, Bruno; Nahum, L. H.; Hoff, Hebbel E.

doi:10.1016/s0002-8703(40)90762-1

Cited by 24 publications

(3 citation statements)

References 4 publications

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“…In experiments performed by Bruno Kisch, L. H. Nahum and H. E. Hoff (20), it is shown that irritation of the heart sur face with minimal chemical or thermic stimuli cause moment arily striking changes in the Ecg., varying in type according to whether the stimulus is applied to the left or the right heart, and very similar to the changes seen and described in coronary cases.…”

Section: Discussionmentioning

confidence: 99%

The Chest Leads in Pericarditis

Groedel¹,

Reichert²

1941

Cardiology

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Section: Discussionmentioning

confidence: 99%

The Chest Leads in Pericarditis

Groedel¹,

Reichert²

1941

Cardiology

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“…It is known from experimental work (Kisch, Nahum, and Hoff, 1940) that the electrocardiographic changes produced by minor surface injury predominate over those due to deep injury, and it follows that persistence of abnormal T vectors after pericardiectomy cannot be taken as a quantitative index of myocardial damage.…”

Section: Eleordiographic Changesmentioning

confidence: 99%

Prognosis after Operation for Constrictive Pericarditis

Portal¹,

Besterman²,

Chambers³

et al. 1966

BMJ

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A survey of the published results of the surgical treatment of constrictive pericarditis (Smith and Muller, 1962) showed a fall ,in the operative mortality from 20% (in 629 patients) before 1950 to 13% (in 776 patients) in the period 1951-61, while the " cures " increased from 44 to 57%. Howeverj the results varied considerably in the 20 series reported since 1950, the operative mortality rate ranging from 3 to 24%. As selection for surgery is bound to be influenced by such figures it was felt that a reappraisal should be made both of the operative risks and of the post-operative course of this condition.In this country the period of the second world war and the succeeding two decades, comprising an epoch of rapid expansion in thoracic surgery, included what will doubtless prove to have been the peak in the number of operations performed for this disease. The back-log of operable cases was largely abolished and the incidence of new ones was possibly curtailed by the advent of antituberculous chemotherapy. The present report covers the operations of patients subjected to pericardiectomy for constriction at two cardiothoracic units since 1942, and includes a recent assessment of those survivors who could be traced for a follow-up e ation.

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“…New observations show that surface injuries to the dog heart produce very much greater changes in the electrocardiogram than do injuries of comparable areas beneath the surface (113). The S-T segment is greatly altered by surface application of 0.2 M po tassium chloride or calcium chloride (not by sodium or magnesium salts), while subsurface injection is nearly without effect.…”

mentioning

confidence: 96%