The predictive value of serum thyroglobulin in the follow-up of differentiated thyroid cancer

Roelants, Véronique; Nayer, Philippe De; Bouckaert, A.; Beckers, Christian

doi:10.1007/bf00879658

Cited by 18 publications

(11 citation statements)

References 25 publications

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“…S-Tg is a well-known serologic marker for persistence or recurrence of DTC (6,12,22); prognostic value of s-Tg for DTC patients with distant metastasis has also been reported (13). As reported in previous studies, patients with s-Tg > 75.8 ng/ml showed poor DSS, when compared to patients with lower s-Tg.…”

Section: Discussionmentioning

confidence: 74%

Distant metastatic lesions in patients with differentiated thyroid carcinoma

Ahn¹,

Jeong²,

Lee³

et al. 2013

Nuklearmedizin

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Section: Discussionmentioning

confidence: 74%

Distant metastatic lesions in patients with differentiated thyroid carcinoma

Ahn¹,

Jeong²,

Lee³

et al. 2013

Nuklearmedizin

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“…The main purpose of the I-131 ablation therapy is removing the residual tissue in the patients with DTC (5,6). Microscopic tumor foci are eradicated as a result of ablation (6).…”

Section: Discussionmentioning

confidence: 99%

“…Microscopic tumor foci are eradicated as a result of ablation (6). The elimination of all residual tissue with ablation increases the sensitivity of WBS by increasing the accumulation of I-131 in the metastatic foci (7).…”

Section: Discussionmentioning

confidence: 99%

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The Effects of the Factors Related to the Patient and the Disease on the Performance of Ablation Therapy in Patients with Differentiated Thyroid Cancer who have Received I-131 Ablation Therapy

Şengöz

Sürücü²,

Demir³

et al. 2012

MIRT

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Objective: To investigate whether the factors related to the patient and the disease have any effect on the success of ablation therapy in patients with differentiated thyroid cancer who have received I-131 ablation therapy.Material and Methods: All the patients with differentiated thyroid cancer were referred for I-131 ablation therapy after thyroidectomy between July 2007 and September 2009. The patients had at least six months of follow-up. Age, gender, type of tumor, presence of capsule invasion, size of tumor, number of the tumors, localization of the tumor, invasion of thyroid capsule, lymph/vessel invasion, presence of metastatic lymph nodes, type of surgery, preablation values of thyroglobulin (Tg), AntiTg, TSH, surveys for the evaluation of metastatic disease, (thyroid and bone scintigraphy, neck and abdominal ultrasonography, chest and brain computerized tomography), administered dose, postablation I-131 whole body scan (WBS) and diagnostic I-131 WBS, neck USG, values of Tg and AntiTg at the 6th month were recorded. The presence of residual thyroid activity on the 6th month diagnostic I-131 WBS image was accepted as the criterion for ablation success.Results: 191 patients with differentiated thyroid cancer were assessed in this study. The overall success rate of the first ablation therapy was 74.3%. The success rate of the ablation therapy was 66% and 75% in metastatic group and non-metastatic group, respectively. Except the significant correlation between the number of pathologic lymph nodes and the success of ablation (p=0.025), there was no other significant correlation between the patient/disease related factors and the success of ablation therapy.Conclusion: Significant correlation between the number of the pathologic lymph nodes and the ablation therapy performance can also be due to statistical error because of the limited sample size. There was no significant correlation between other patient/disease related prognostic factors and the success of ablation therapy.Conflict of interest:None declared.

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“…Assim, ela não deve ser detectada em pacientes com total ablação da tireóide 6 . A detecção de Tg após a elevação do TSH ou rhTSH nesses pacientes, indica a presença de doença em atividade, seja persistente ou recorrente com sensibilidade sob supressão hormonal de 88%, especificidade de 99% e acurácia de 96,5% 65,66 . Tem sido um marcador tumoral muito utilizado no seguimento clínico, mensurado após injeção intramuscular do hormônio estimulante da tireóide recombinante (rhTSH), ou após a suspensão dos hormônios tireoideanos com elevação do TSH natural 62,67,68 .…”

Section: Mensuração Da Tireoglobulina Séricaunclassified

Investigação de metástases não funcionantes em câncer de tireóide com sestamibi-99mTc e iodo-131

Gonçalves¹

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The predictive value of serum thyroglobulin in the follow-up of differentiated thyroid cancer

Cited by 18 publications

References 25 publications

Distant metastatic lesions in patients with differentiated thyroid carcinoma

Distant metastatic lesions in patients with differentiated thyroid carcinoma

The Effects of the Factors Related to the Patient and the Disease on the Performance of Ablation Therapy in Patients with Differentiated Thyroid Cancer who have Received I-131 Ablation Therapy

Investigação de metástases não funcionantes em câncer de tireóide com sestamibi-99mTc e iodo-131

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