The predictive value of metabolic response to preoperative radiochemotherapy in locally advanced rectal cancer measured by PET/CT

Abstract

Metabolic response to a preoperative RCTX using FDG-PET/CT in rectal cancer patients can be correlated with histopathological response, but FDG uptake of peritumoral inflammation cells limited the results and led to false negative results.

Prognostic stratification using F-18 FDG PET/CT in patients with advanced stage (Stage III and IV) non-small cell lung cancer

“…Recent studies mainly investigated the relationships of the changes of SUV after treatment and pathologic response in various tumors including NSCLC [6,[24][25][26]. However, these studies also investigated the primary tumor SUV values effect on prognosis and whether the changes of SUV values after treatment could predict pathologic response to treatment.…”

Textural Parameters of Tumor Heterogeneity in 18F-FDG PET/CT for Therapy Response Assessment and Prognosis in Patients with Locally Advanced Rectal Cancer

“…As reported earlier (15), the inclusion criteria were biopsyproven rectal adenocarcinoma between 0 and 15 cm from the anal verge, an endosonographic tumor stage of uT3 with or without local lymph node metastases, no distant metastases, no previous chemotherapy or radiation therapy, a Karnofsky index of more than 60%, and normal liver and kidney function. The exclusion criteria were a history of other malignancies, diabetes mellitus, lack of compliance, and contraindications to nRCT.…”

“…Standardized uptake value (SUV) analysis of this patient population for response assessment was published in previous articles (15,17).…”

Value of diffusion-weighted imaging in the detection of viable tumour after neoadjuvant chemoradiation therapy in patients with locally advanced rectal cancer: comparison withT2weighted and PET/CT imaging

“…Many investigators have reported a substantial decrease in standardised uptake value (SUV) post-CRT in responders compared with nonresponders [19][20][21][22]. However, only a few studies have compared the abilities of MRI and PET/CT to enable prediction of responses to neoadjuvant CRT [23,24].…”