The Predictive Value of Brachial-Ankle Pulse Wave Velocity in Coronary Atherosclerosis and Peripheral Artery Diseases in Urban Chinese Patients

Abstract

Coronary artery disease (CAD) isbaseline data for each patient. All patients underwent cardioangiography and were divided into four groups according to their Gensini scores: a control group, and groups with a mild, moderate, or severe degree of stenosis. One hundred and five of these patients simultaneously underwent angiography of the lower extremities and were divided into four groups according to the degree of artery stenosis: a control group, and groups with a mild, moderate, or severe degree of stenosis. Grouping of baPWV levels was made according to Japanese surveys. Bilateral baPWV and ABI were measured using non-invasive arterial atherosclerosis measuring equipment. In the coronary artery groups based on Gensini score, ABI in the group with a high degree of stenosis was significantly lower than that in the control and moderate stenosis groups, while the baPWV was significantly higher than that in the control and mild stenosis groups. In the grouping of baPWV levels, it was indicated that the ABI level was significantly different between each group. The ABI <0.9 in groups with baPWV <1,400 cm/s and >2,100 cm/s was higher than that in other groups. In the grouping by angiography of the lower extremities, the ABI level was decreased with increasing degree of artery stenosis while the baPWV levels were increased under the same circumstance (p <0.05 or p <0.01). Logistic regression analysis indicated that relatively low ABI, high baPWV, abnormal fasting blood glucose, and smoking were independent risk factors for the development of cardiovascular diseases. The simultaneous measurement of bilateral baPWV and ABI using the newly developed equipment presented herein is

Prediction of Coronary Artery Disease Using Pulse Wave Velocity and Retinal Artery Lesions

“…Tso et al (2005) observed that patients diagnosed as lupus erythematosus with baPWV above 1,400 cm/s had more cardiovascular risk factors. Xu et al (2008) demonstrated that baPWV above 1,600 cm/s strongly indicated severe coronary atherosclerosis in elderly urban Chinese patients, and Kim et al (2009) showed cutoff value of 1,635 cm/s was useful for predicting the presence of multiple coronary artery occlusive disease. In the present study we demonstrated that in patients with baPWV over 1,400 cm/s, the number of those diagnosed as CAD is significantly more than those diagnosed as non-CAD.…”

Arterial Stiffness Measured as Pulse Wave Velocity is Highly Correlated with Coronary Atherosclerosis in Asymptomatic Patients

“…Imanishi R et al revealed that a high ba-PWV level (mean: 18.9 m/s vs. 15.2 m/s) is an independent predictor of the presence of CAD in men with suspected heart disease 20) . Xu et al showed that in suspected CAD patients, a ba-PWV 18.0 m/s often follows a severe coronary event 21) . Our study revealed that in asymptomatic patients, ba-PWV at 15.64 m/s had a sensitivity of 64.5%, specificity of 65.6%, and an AUC of 0.662 in predicting coronary artery stenosis.…”

Reference value of brachial-ankle pulse wave velocity for the eastern Chinese population and potential influencing factors

“…To date, the methods for evaluating arterial function are very limited; therefore, the clinical significance of noninvasive evaluation of early vascular diseases has attracted more attention. Increasing arterial stiffness is a pathological state of vascular damage, and is closely associated with atherosclerotic cardiovascular diseases, such as coronary artery disease (19,20). Pulse wave velocity is widely used as an indicator of arterial stiffness, and it has been shown that PWV is also Data are reported as means ± SD, except for baPWV.…”