BACKGROUND: Implications of entrepreneurial education (EE), entrepreneurial self-efficacy (ESE) and personality traits (PT) on the entrepreneurial intentions of the deaf is yet unknown in existing literature. OBJECTIVE: To examine the influence of EE, ESE and PT on the entrepreneurial intentions among some 250 Deaf and Hard of hearing (DHH) students from two post-secondary institutions in Oyo state, Nigeria. METHODS: A descriptive research design was adopted, while a structured paper questionnaire was used for data collection. The data generated were analysed using descriptive statistics and the inferential statistics of Pearson Product Moment Correlation and hierarchical multiple regression at a 0.05 level of significance. RESULTS: The entrepreneurial intentions of DHH college students had a significant positive correlation with EE (r = 0.18, p < 0.05), agreeableness (r = 0.23, p < 0.05), and conscientiousness (r = 0.19, p < 0.05); but had a negative correlation with ESE, neuroticism and openness. Furthermore, personality traits and ESE were the highest predictors of entrepreneurial intention among DHH college students. CONCLUSIONS: Personality traits were the greatest predictor of the entrepreneurial intention of DHH college students post the COVID-19 lockdowns in Nigeria. Therefore, higher education institutions should intensify their efforts in entrepreneurial education and parents of DHH students should encourage them to seek entrepreneurial opportunities.