The Prediction of Adverse Maternal Outcomes in Preeclampsia

Prediction of progression to severe disease in women with late preterm hypertensive disorders of pregnancy

“…These were not available in the HYPITAT‐II data. However, subjective maternal symptoms are non‐quantifiable parameters and therefore the model would probably be more exact by not using these predictors . The type of hypertensive disorder was not frequently used as predictor in other prediction models.…”

“…We evaluated whether our primary outcome measure (HDP as indication for delivery) could be predicted with several characteristics at hospital admission. Candidate predictors were selected based on previous studies . Selected predictors were maternal characteristics (ethnicity, maternal age, education, smoking), clinical characteristics (diastolic BP, systolic BP, body mass index, gravidity, parity, gestational age at diagnosis, previous abortion, previous cesarean section, type of HDP, history of HDP, comorbidity) or laboratory findings (proteinuria, ALT, AST, LDH, creatinine, uric acid, platelets, hematocrit, hemoglobin) measured at baseline.…”

Clinical significance of serum albumin level in pregnancy‐related hypertension

“…There have been many clinical studies to determine the predictors for pregnancy outcome and neonatal prognosis, such as blood pressure, serum or urine uric acid, microalbuminuria, proteinuria, platelet count, C‐reactive protein (CRP), and LDH, in pregnant women with preeclampsia 7–12 . Among these prognosis factors, evaluating 24‐h proteinuria has been shown to be most important in differentiating preeclampsia from gestational hypertension or chronic hypertension, and is associated with disease severity and pregnancy outcome 13 .…”

Accuracy of liver function tests for predicting adverse maternal and fetal outcomes in women with preeclampsia: a systematic review

“…Studies that defined women as having ‘preeclampsia’ were included. The various definitions for preeclampsia are provided in Table 1. Index test: LFTs including AST, ALT, lactate dehydrogenase (LDH), gamma glutamyl transferase (GGT), alkaline phosphatase (ALP) and bilirubin. Composite adverse outcome: Maternal outcome included one of the following; eclampsia, pulmonary edema, maternal death, abruption, disseminated intravascular coagulation (DIC), renal failure, intracerebral hemorrhage, adult respiratory distress syndrome,or retinal detachment (7,12). Fetal outcome that included one of the following; neonatal deaths, fetal distress, intrauterine growth restriction, intraventricular hemorrhage, respiratory distress syndrome, mechanical ventilation, necrotizing enterocolitis,or bronchopulmonary dysplasia (7).…”