The prediction model of fatty liver was established by blood biochemical indexes

Abstract

Background The main cause of chronic liver disease is fatty liver, which includes alcoholic fatty liver and non-alcoholic fatty liver disease. This study is aimed to establish the prediction model of fatty liver, and provide help for the prevention and treatment of fatty liver, especially NAFLD in the future. Methods Datasets from 2017 to March 2020 NHANES required for the analysis were downloaded from the NHANES web site and R 4.1.1. Software was used for data analysis. A total of 3762 subjects were enrolled in this study, which were divided into model construction group and model validation group in a 2:1 ratio. Results The study selected 6 indicators to build the prediction model, which are as follows: ALT, Platelet count, Creatinine, LDH, HS C-Reactive Protein, Glucose. Then the prediction model was constructed. The area under ROC curve of the model was 0.7471. In the validation population, the area under the ROC curve of the model was 0.7816. Conclusions F score has a good predictive effect on fatty liver, which can be used as an important means for the prevention and treatment of fatty liver, especially NAFLD in the future.