The precise modification of a nanoscaled Keplerate-type polyoxometalate with NH₂-groups: reactive sites, mechanisms and dye conjugation

Abstract

The interaction of alkoxysilanes with nanoscaled giant polyoxoclusters is a challenging route for efficiently building blocks for supramolecular smart-tune design. 3-aminopropyltrimethoxysilane (APTMS) treatment grafts amino groups onto the surface of...

Melem Nanorectangular Prism-Modified {Mo72Fe30} Nanocapsule as a Visible-Light-Assisted Photocatalyst for Catalase-Like Activity

“…They attracted a large volume of attention because of their unique structures and extensive applications in catalysis, medicine, materials, energy conversion, and molecular electronics . POMs could be combined with other substrates in a nanocomposite structure to modify their structure and light properties. , Recently, giant POMs as metal–oxide frameworks (MOFs) have been of extreme interest for their catalytic and photocatalytic activity . Nanoscale Keplerates ({Mo 132 }, {Mo 72 Fe 30 }, {Mo 72 Cr 30 }, and {Mo 72 V 30 }) have been exploited by different groups including us to catalyze different reactions. − We have also recently discovered the effective photocatalytic activity of Keplerate {Mo 72 Fe 30 } in H 2 O 2 dismutation and dye degradation .…”

“…Just recently, we discovered that encapsulation of the Keggin H 3 PMo 12 O 40 into the Keplerate {Mo 72 Fe 30 } shell improved the photocatalytic activity of the resulting core–shell cluster . Combining {Mo 72 Fe 30 } with the appropriate organic or inorganic materials is another solution that could modify its properties and promote its catalytic and photocatalytic activity. The electron-capturing ability of POMs makes them appropriate electron relays (reservoir) in conjunction with the electron release of organic compounds .…”

Tetrahedral Keggin Core Tunes the Visible Light-Assisted Catalase-Like Activity of Icosahedral Keplerate Shell

“…They can be formed by replacing 30 Mo 2 O 4 Ac linkers in {Mo 132 } with 30 Fe aq 3+ in crystalline forms including discrete molecules, interconnected one-dimensional chains, or two-dimensional layers. , They can also be prepared directly by mixing acidic solutions of FeCl 3 and NaMoO 4 , producing immediately an amorphous phase of cluster . {Mo 72 Fe 30 } can be used as a unique shell for hosting some clusters such as Lindqvist and Keggin polyoxomolybdates in both reduced and oxidized forms. − They have been limitedly used as catalysts for the growth of monolayer carbon nanotubes, water oxidation, and oxidation of sulfides, alcohols, and olefins. − Just recently, we functionalized its surface with amino groups in a controlled manner …”

The Electrostatic‐Mediated Formation of a Coordination Complex: the Trapping and Release of an Antitumor Drug with an Anthracycline Core from {Mo72Fe30}‐Based Ensembles

“…[10] Due to their flexible functionalization via isostructural substitution, [11] electrostatic interaction [12] or covalent modification, one can tune the hydrophilic-hydrophobic properties or photoinduced charge transfer process in giant POM nanoclusters. [13][14][15][16][17][18] Some polyoxometalates demonstrate biological activity, including antitumor, antiviral and antibacterial. [19][20][21][22][23] O.…”

“…Binding drugs to {Mo 72 Fe 30 } is possible either via direct linking through coordinate, electrostatic, or van-der-Waals interactions/H-bonds (as with vitamin B 1 , insulin, [36] and NO x species), [37] and through covalent linkers (NH 2 groups, grafted onto the surface of cluster, can serve this purpose). [15] To ensure the targeted delivery of this POM-based system to the diseased organ, a recognition vector can be anchored on the Keplerate's surface. By using the iontophoresis of multicharged {Mo 72 Fe 30 }, one can achieve highly accurate treatment and even form a depot to prolong the release of the associate drug.…”