The Precise Dapt Score Can Be Used to Refine Risk Stratification and Predict Short and Long-Term Mortality in Acute Mi Patients

Use of PRECISE-DAPT Score and Admission Platelet Count to Predict Mortality Risk in Patients With Acute Coronary Syndrome

“…4 However, data coming from retrospective registries have suggested that the PRECISE-DAPT score may also perform well as a stratification tool for in-hospital and long-term mortality. 9,10 This might partly be explained by the inclusion of variables that have been shown to be strongly associated with clinical thrombotic and bleeding events after short and long follow-up. 33,[35][36][37][38][39][40][41][42][43][44][45][46][47][48][49] Moreover, a recent retrospective registry has shown a significant association between the PRECISE DAPT score and the extension of coronary artery disease as evaluated by the Gensini score, 50 being able to discriminate patients at high risk of further ischemia.…”

“…This might explain why data from retrospective registries suggested that the PRECISE-DAPT score might also help risk-stratify patients for mortality; previous studies have also suggested a noninferior performance compared to the Thrombolysis in Myocardial Infarction risk score with regard to in-hospital mortality. 9,10 Platelets play a crucial role in several processes beyond hemostasis and thrombosis, such as inflammation, wound healing, angiogenesis, and maintenance of vascular integrity. 11 Through their interaction with other cellular effectors of both innate and adaptive immunity, platelets have emerged as modulators of progression of both atherosclerosis and atherothrombosis.…”

“…This might explain why data from retrospective registries suggested that the PRECISE-DAPT score might also help risk-stratify patients for mortality; previous studies have also suggested a noninferior performance compared to the Thrombolysis in Myocardial Infarction risk score with regard to in-hospital mortality. 9,10…”