The powerful Solanaceae: Food and nutraceutical applications in a sustainable world

Añibarro-Ortega, Mikel; Pinela, José; Αλεξόπουλος, Αλέξιος; Petropoulos, Spyridon Α.; Ferreira, Isabel C.F.R.; Barros, Lillian

doi:10.1016/bs.afnr.2022.03.004

Cited by 11 publications

(6 citation statements)

References 158 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The plants and culture of Solanum lycopersicum and Solanum tuberosum , along with other species from the Solanum , Capsicum , and Nicotiana genera, have been extensively studied due to their agricultural and/or nutritional importance, as well as their suitability as model organisms ( Kimura and Sinha, 2008 ; Pombo et al, 2020 ; Bánfalvi et al, 2021 ). These plants are of significant interest in scientific research and breeding programs due to their economic value, widespread cultivation, and diverse applications in the food industry ( Añibarro-Ortega et al, 2022 ). The identification of CPI sequences primarily in the Solanum , Capsicum , and Nicotiana genera aligns with the focus on these agriculturally important species.…”

Section: Discussionmentioning

confidence: 99%

Carboxypeptidase inhibitors from Solanaceae as a new subclass of pathogenesis related peptide aiming biotechnological targets for plant defense

Gomes,

Espósito,

Baracat-Pereira

2023

Front. Mol. Biosci.

View full text Add to dashboard Cite

Background: Plant protease inhibitors play a crucial role in inhibiting proteases produced by phytopathogens and exhibiting inhibitory effects on nematodes, fungi, and insects, making them promising candidates for crop protection. Specifically, carboxypeptidase inhibitors, a subset of proteinase inhibitors, have been extensively studied in potato and tomato of Solanaceae plant family. However, further research is needed to fully understand the functions and biotechnological potential of those inhibitors in plants. This work aimed to in silico characterize carboxypeptidase inhibitors from Solanaceae as potential antimicrobial and defense agents focused on biotechnological targets.Methods: The methodology employed involved search in UniProt, PDB, KNOTTIN, NCBI, and MEROPS databases for solanaceous carboxypeptidase inhibitors, phylogenetic relationships and conservation patterns analyzes using MEGA-X software and Clustal Omega/MView tools, physicochemical properties and antimicrobial potential prediction using ProtParam, ToxinPred, iAMPred, and APD3 tools, and structural features prediction using PSIPRED.Results and discussion: A systematic literature search was conducted to identify relevant studies on Solanaceae carboxypeptidase inhibitors and their activities against pathogens. The selected studies were reviewed and the main findings compiled. The characterization of Solanaceae carboxypeptidase inhibitors proposed for the first time the global sequence consensus motif CXXXCXXXXDCXXXXXCXXC, shedding light on carboxypeptidase inhibitors distribution, sequence variability, and conservation patterns. Phylogenetic analysis showed evolutionary relationships within the Solanaceae family, particularly in Capsicum, Nicotiana, and Solanum genera. Physicochemical characteristics of those peptides indicated their similarity to antimicrobial peptides. Predicted secondary structures exhibited variations, suggesting a broad spectrum of action, and studies had been demonstrated their activities against various pathogens.Conclusion: Carboxypeptidase inhibitors are being proposed here as a new subclass of PR-6 pathogenesis-related proteins, which will aid in a focused understanding of their functional roles in plant defense mechanisms. These findings confirm the Solanaceae carboxypeptidase inhibitors potential as defense agents and highlight opportunities for their biotechnological applications in pathogen control.

show abstract

Section: Discussionmentioning

confidence: 99%

Carboxypeptidase inhibitors from Solanaceae as a new subclass of pathogenesis related peptide aiming biotechnological targets for plant defense

Gomes,

Espósito,

Baracat-Pereira

2023

Front. Mol. Biosci.

View full text Add to dashboard Cite

show abstract

“…There are now various and more advanced studies on its genome, molecular biology, etc. [ 1 , 2 , 3 ]. Compared with important botanical families of horticultural fruit crops, the Solanaceae family includes several economically important vegetable crops, some of which were described above, with this species representing an important component of human diets worldwide; however, S. muricatum is one of the few new fruit crops of the Solanaceae family that have been successfully adopted by international markets in recent years.…”

Section: Introductionmentioning

confidence: 99%

Systematic Investigation of TCP Gene Family: Genome-Wide Identification and Light-Regulated Gene Expression Analysis in Pepino (Solanum Muricatum)

Zhan

Wang

et al. 2023

Cells

View full text Add to dashboard Cite

Plant-specific transcription factors such as the TCP family play crucial roles in light responses and lateral branching. The commercial development of S. muricatum has been influenced by the ease with which its lateral branches can be germinated, especially under greenhouse cultivation during the winter with supplemented LED light. The present study examined the TCP family genes in S. muricatum using bioinformatics analysis (whole-genome sequencing and RNA-seq) to explore the response of this family to different light treatments. Forty-one TCP genes were identified through a genome-wide search; phylogenetic analysis revealed that the CYC/TB1, CIN and Class I subclusters contained 16 SmTCP, 11 SmTCP and 14 SmTCP proteins, respectively. Structural and conserved sequence analysis of SmTCPs indicated that the motifs in the same subcluster were highly similar in structure and the gene structure of SmTCPs was simpler than that in Arabidopsis thaliana; 40 of the 41 SmTCPs were localized to 12 chromosomes. In S. muricatum, 17 tandem repeat sequences and 17 pairs of SmTCP genes were found. We identified eight TCPs that were significantly differentially expressed (DETCPs) under blue light (B) and red light (R), using RNA-seq. The regulatory network of eight DETCPs was preliminarily constructed. All three subclusters responded to red and blue light treatment. To explore the implications of regulatory TCPs in different light treatments for each species, the TCP regulatory gene networks and GO annotations for A. thaliana and S. muricatum were compared. The regulatory mechanisms suggest that the signaling pathways downstream of the TCPs may be partially conserved between the two species. In addition to the response to light, functional regulation was mostly enriched with auxin response, hypocotyl elongation, and lateral branch genesis. In summary, our findings provide a basis for further analysis of the TCP gene family in other crops and broaden the functional insights into TCP genes regarding light responses.

show abstract

“…Eggplant (Solanum melongena L.) is an economically important crop in the genus Solanum (family Solanaceae) [21]. Eggplant has a long history of cultivation in Asia, Africa, Europe, and other regions [22].…”

Section: Introductionmentioning

confidence: 99%

Genome-Wide Analysis of the Mads-Box Transcription Factor Family in Solanum melongena

Chen

Yang

2023

IJMS

View full text Add to dashboard Cite

The MADS-box transcription factors are known to be involved in several aspects of plant growth and development, especially in floral organ specification. However, little is known in eggplant. Here, 120 eggplant MADS-box genes were identified and categorized into type II (MIKCC and MIKC*) and type I (Mα, Mβ, and Mγ) subfamilies based on phylogenetic relationships. The exon number in type II SmMADS-box genes was greater than that in type I SmMADS-box genes, and the K-box domain was unique to type II MADS-box TFs. Gene duplication analysis revealed that segmental duplications were the sole contributor to the expansion of type II genes. Cis-elements of MYB binding sites related to flavonoid biosynthesis were identified in three SmMADS-box promoters. Flower tissue-specific expression profiles showed that 46, 44, 38, and 40 MADS-box genes were expressed in the stamens, stigmas, petals, and pedicels, respectively. In the flowers of SmMYB113-overexpression transgenic plants, the expression levels of 3 SmMADS-box genes were co-regulated in different tissues with the same pattern. Correlation and protein interaction predictive analysis revealed six SmMADS-box genes that might be involved in the SmMYB113-regulated anthocyanin biosynthesis pathway. This study will aid future studies aimed at functionally characterizing important members of the MADS-box gene family.

show abstract

The powerful Solanaceae: Food and nutraceutical applications in a sustainable world

Cited by 11 publications

References 158 publications

Carboxypeptidase inhibitors from Solanaceae as a new subclass of pathogenesis related peptide aiming biotechnological targets for plant defense

Carboxypeptidase inhibitors from Solanaceae as a new subclass of pathogenesis related peptide aiming biotechnological targets for plant defense

Systematic Investigation of TCP Gene Family: Genome-Wide Identification and Light-Regulated Gene Expression Analysis in Pepino (Solanum Muricatum)

Genome-Wide Analysis of the Mads-Box Transcription Factor Family in Solanum melongena

Contact Info

Product

Resources

About