2022
DOI: 10.7759/cureus.32366
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The Potential Threat of Vertical Transmission in Methicillin-Resistant Staphylococcus Aureus Infection: A Systematic Review 2022

Abstract: This systematic review paper aimed to assess and analyze the prevalence of maternal colonization of Staphylococcus aureus (S. aureus) also known as methicillin-sensitive Staphylococcus aureus (MSSA) and methicillin-resistant Staphylococcus aureus (MRSA) in the peripartum period and its significance on vertical transmission to the neonate and if it is a potential threat to the health of newborns. For this, multiple databases, such as PubMed, MEDLINE, ScienceDirect, and the database of Elsevier, were used to sco… Show more

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Cited by 2 publications
(3 citation statements)
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“… 6 The prevalence of MRSA carriage in vaginal sites of pregnant women is 1.7% and 5.7% in anterior nares showed the neonatal incidence of MRSA carriage is 0.8%. 7 , 8 There are many risk factors for MRSA colonization in neonates including low birth weight, prematurity and multiple gestation. 6 Advanced maternal age and lack of access to proper healthcare facilities during pregnancy are the leading risk factors for maternal colonization.…”
Section: Introductionmentioning
confidence: 99%
See 1 more Smart Citation
“… 6 The prevalence of MRSA carriage in vaginal sites of pregnant women is 1.7% and 5.7% in anterior nares showed the neonatal incidence of MRSA carriage is 0.8%. 7 , 8 There are many risk factors for MRSA colonization in neonates including low birth weight, prematurity and multiple gestation. 6 Advanced maternal age and lack of access to proper healthcare facilities during pregnancy are the leading risk factors for maternal colonization.…”
Section: Introductionmentioning
confidence: 99%
“…Since MRSA colonization from healthcare workers or household contacts is possible, there should be identification of all environmentally and maternal derived risk factors. 8 …”
Section: Introductionmentioning
confidence: 99%
“…6 Colonization with S. aureus in peripartum patients is common and has been associated with invasive infections-such as skin and soft tissue infections, mastitis, pneumonia, and sepsis-as well as vertical transmission, and adverse neonatal outcomes. [7][8][9][10] Moreover, a prolonged course of intravenous antibiotics is often needed for patients with S. aureus bloodstream infections, including through peripherally inserted central lines, which are at increased risk of infectious and thromboembolic complications during pregnancy. 11 S. aureus infections in pregnancy have also been linked to significant healthcare utilization and subsequent economic burden.…”
mentioning
confidence: 99%