The potential role of sleep in sexual dysfunction in patients with schizophrenia

Boin, André Campiolo; Nozoe, Karen Tieme; Polesel, Daniel Ninello; Andersen, Mônica Levy; Tufik, Sérgio

doi:10.1016/j.schres.2014.01.042

Cited by 5 publications

(4 citation statements)

References 11 publications

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“…Sexual dysfunction is a common problem in people with mood disorders, 1 schizophrenia, and other psychotic disorders, with reported prevalence rates of 30%–80% in women and 45%–80% in men. 2 – 4 In clinical practice, sexual disorders are found as a complication in people treated with antipsychotics. The prevalence rate of sexual disorders in men treated with antipsychotics is estimated to be 54% ( Figure 1 ).…”

Section: Introductionmentioning

confidence: 99%

The influence of atypical antipsychotic drugs on sexual function

Just¹

2015

NDT

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Human sexuality is contingent upon many biological and psychological factors. Such factors include sexual drive (libido), physiological arousal (lubrication/erection), orgasm, and ejaculation, as well as maintaining normal menstrual cycle. The assessment of sexual dysfunction can be difficult due to the intimate nature of the problem and patients’ unwillingness to discuss it. Also, the problem of dysfunction is often overlooked by doctors. Atypical antipsychotic treatment is a key component of mental disorders’ treatment algorithms recommended by the National Institute of Health and Clinical Excellence, the American Psychiatric Association, and the British Society for Psychopharmacology. The relationship between atypical antipsychotic drugs and sexual dysfunction is mediated in part by antipsychotic blockade of pituitary dopamine D2 receptors increasing prolactin secretion, although direct correlations have not been established between raised prolactin levels and clinical symptoms. Variety of mechanisms are likely to contribute to antipsychotic-related sexual dysfunction, including hyperprolactinemia, sedation, and antagonism of a number of neurotransmitter receptors (α-adrenergic, dopaminergic, histaminic, and muscarinic). Maintaining normal sexual function in people treated for mental disorders can affect their quality of life, mood, self-esteem, attitude toward taking medication, and compliance during therapy.

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Section: Introductionmentioning

confidence: 99%

The influence of atypical antipsychotic drugs on sexual function

Just¹

2015

NDT

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“…However, it may be more challenging for those adolescents who have a psychiatric disorder because factors associated with the disorder (eg, low self-esteem, enduring mental health-related stigma and social exclusion) may interfere with the ability to form relationships and obtain sexual experiences. 4,5,6,7,8 Problems related to sexuality can have a profound impact on quality of life in general. 9,10,11,12 The available literature on sexuality among youth with psychiatric conditions is primarily focused on negative and risky behaviors rather than healthy sexual development.…”

Section: Introductionmentioning

confidence: 99%

Talking About Sexuality with Youth: A Taboo in Psychiatry?

Bungener

Post

Berends

et al. 2022

The Journal of Sexual Medicine

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Background: Young people who have psychiatric problems are more likely than their peers to endure difficulties during their sexual and gender identity development.Aim: This study aims to examine the communication between mental health care providers and their patients about the topics of relations, sexuality and gender identity, including a description of professionals' attitudes toward these topics and the factors that contribute to and inhibit communication. Methods: Study participants (n = 242, response rate = 31%) were a representative sample of a large multicenter cohort of 768 mental health care professionals (eg, medical doctors, psychiatrists, psychologists, group counselors, parent counselors) of 7 institutions and 5 solo practices in the Netherlands, who completed a survey on communication about sexuality and gender identity with their young patients (age 12−21 years). Outcomes: Sexuality and gender identity are infrequently discussed by mental health care providers with their young patients or their patients' parents.Results: Of the study sample, 99.5 % valued sexuality as an important topic to discuss with their patients. However, only 17.1% of the professionals reported that they discussed sexuality-related issues with the majority (>75%) of their patients (adolescents: 19.9%, parents: 14.4%) Additionally, only 2.3 % of the participants discussed gender nonconformity regularly with patients. Information about sexual side effects of prescribed medication was infrequently (20.3%) provided: antidepressants (40.0%), antipsychotics (34.0%), benzodiazepines (5.1%) and stimulants (2.4%). The most frequently cited reasons for not discussing these topics were a lack of awareness, own feelings of discomfort, and the patients' supposed feelings of shame. There was no gender differences observed. Clinical implications: Recommendations for professionals include to be aware of these topics, initiating ageappropriate conversation and use inclusive language. Strengths and limitations: The present study included a diverse and representative group of mental health care professionals. Frequency of sexual communication was based on self-report, which brings a risk of bias. Conclusion: Despite a recognized need to engage in age-appropriate communication about sexuality and gender identity in youth mental health care, mental health providers seem to remain hesitant to discuss such topics. Bungener SL,

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“…Accumulating evidence from studies with samples of postmenopausal women, fibromyalgia patients, shift workers, and schizophrenia patients has shown the significant association between sexual dysfunction and sleep disturbance. [ 22 – 25 ] Given the high prevalence of sleep problem in methadone-maintained patients, sleep disturbance may impair the sexual function, leading to the high prevalence of sexual dysfunction in methadone-maintained patients. However, such association is understudied in methadone patients.…”

Section: Introductionmentioning

confidence: 99%

Poor sleep quality is significantly associated with low sexual satisfaction in Chinese methadone-maintained patients

Zhang

Zhu

et al. 2017

Medicine

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Sleep disturbance negatively affects sexual function. Sleep problem and sexual dysfunction are common in methadone-maintained patients; however, their association is understudied in this patient population.This study examined the association between sleep quality and sexual satisfaction in Chinese patients receiving methadone maintenance treatment (MMT).This was a cross-sectional study. A total of 480 MMT patients who had sex with their sex partners within 1 month before the survey were recruited from 3 MMT clinics in Wuhan, China. Sexual satisfaction was assessed with a single question, and sociodemographic and clinical data were collected with a standardized questionnaire. Sleep quality was assessed with the Pittsburgh Sleep Quality Index. Multiple ordinary logistic regression was used to control for potential confounders that may bias the sleep-sexual satisfaction relationship.Sexual satisfaction scores were significantly higher in poor sleepers than normal sleepers (3.2 ± 0.9 vs. 2.8 ± 1.0, t = 4.297, P < .001). After controlling for potential confounders, results of the multiple regression analysis reveal that poor sleep quality was still significantly and independently associated with low sexual satisfaction (odd ratio = 1.58, P = .009).Poor sleep quality is significantly associated with low sexual satisfaction of methadone-maintained patients. Improving sleep quality might improve sexual satisfaction of patients receiving MMT.

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The potential role of sleep in sexual dysfunction in patients with schizophrenia

Cited by 5 publications

References 11 publications

The influence of atypical antipsychotic drugs on sexual function

The influence of atypical antipsychotic drugs on sexual function

Talking About Sexuality with Youth: A Taboo in Psychiatry?

Poor sleep quality is significantly associated with low sexual satisfaction in Chinese methadone-maintained patients

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