The Potential of Natural Compounds Regulating Autophagy in the Treatment of Osteoporosis
Yiwei Zhao,
Zechao Qu,
Songchuan Zhao
et al.
Abstract:The maintenance of bone homeostasis is dynamically regulated by osteoblast-mediated bone formation and osteoclast-mediated bone resorption. Abnormal differentiation of osteoclast and insufficient osteoblast production can cause bone diseases such as osteoporosis. As one of the highly conserved catabolic pathways in eukaryotic cells, autophagy plays an important role in maintaining cell homeostasis, stress injury repair, proliferation and differentiation. Numerous studies have found that autophagy activity is e… Show more
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