The potential of electrocardiography for cardiac risk prediction in chronic and end-stage kidney disease

Skampardoni, Sofia; Poulikakos, Dimitrios; Malík, Marek; Green, Darren; Kalra, Philip A.

doi:10.1093/ndt/gfz166

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“…In a study conducted at 5 Brazilian centers including 309 patients with CKD stages 3 and 4, the estimated risk of LVH was found to be 53% and of them, 60% were in Stage 4 CKD. This empirical evidence emphasizes the need for stringent diagnosis of CKD in order to prevent the occurrence of LVH before dialysis which will decrease the disease rate of CVD in such group [22] . In a study, LVH existed in 68-89% of patients before the advent of dialysis [23].…”

Section: Introductionmentioning

confidence: 98%

Left Ventricular Hypertrophy (LVH) in Patients with Advanced Stages of Chronic Kidney Disease (CKD)

Khan

Begum

Raza

et al. 2021

JPRI

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Objective: To determine the left ventricular hypertrophy (LVH) prevalence in patients admitted with advanced stage of Chronic kidney disease at Ziauddin hospital. Methodology: This was a cross-sectional study conducted in department of Nephrology of Ziauddin University Hospital, Karachi from January to July 2016. The inclusion criteria involved patients with CKD stages 3-5 undergoing two-dimensional M mode Doppler echocardiography. The sample size of the study was 147. LVH was considered as positive when Inter-ventricular-septal-wall-thickness in diastole (IVSd) >11 mm, Left-Ventricular-Septal-Wall-Thickness in diastole (LVPWd) >11 mm and Left-Ventricular-Mass-Index (LVMi) >131 g/m2 for men and > 100 g/m2 for women. The exclusion criteria included patients with terminal illness, on mechanical ventilator support, valvular heart diseases and congenital heart diseases, liver diseases and patients with acute kidney injury on chronic kidney disease. Results: 88 male and 59 female patients were included. The mean duration of CKD was 7.02±1.60 years. 94(63.9%) study subjects were observed with left ventricular hypertrophy. A significant association of LVH was observed with gender and CKD Stages. Conclusion: LVH can be easily diagnosed and assessed by M-mode or 2D echocardiography. The prevalence was high (60.5%) in stage 3–5 CKD patients.

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Section: Introductionmentioning

confidence: 98%