The Potential of Cytotherapeutics in Hematologic Reconstitution and in the Treatment and Prophylaxis of Graft-Versus-Host Disease. Chapter II: Emerging Transformational Cytotherapies
Abstract:Hematopoietic stem cell transplantation (HSCT) is a life-saving treatment for inherited anemias, immunodeficiencies or hematologic malignancies. A major complication of allo-HSCT associated with high transplant-related mortality rates is graft-versus-host disease (GvHD). Current and future clinical benefits in HSCT enabled by advances in hematopoietic stem cells, mesenchymal stem cells, Tregs and natural killer cells technologies are reviewed here and discussed. Among these evolutions, based on the need for me… Show more
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