The potential impact of nutritional intake on symptoms severity in patients with comorbid migraine and irritable bowel syndrome

Magdy, Rehab; Eid, Ragaey A; Hassan, Mahmoud O.; Mohamed, Abdelrahman; Sayed, Asmaa F El; Mohammed, Zeinab; Hussein, M. M.

doi:10.1186/s12883-022-02723-0

Cited by 6 publications

(5 citation statements)

References 35 publications

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“…A total of 23,643 citations were retrieved from which 7639 duplicates were removed using EndNote 20 and Covidence, resulting in a final set of 16,004 citations/abstracts for review. Following screening, 615 articles were retrieved for full‐text review from which 63 full‐text articles comprised of 52,105 participants ( N = 8720 IBS, N = 43,385 controls) were ultimately included 11,14,15,43–102 . Agreement between authors was almost perfect (kappa statistic = 0.96).…”

Section: Resultsmentioning

confidence: 99%

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A systematic review and meta‐analysis of diet and nutrient intake in adults with irritable bowel syndrome

Veraza,

Calderon,

Jansson‐Knodell

et al. 2023

Neurogastroenterology Motil

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BackgroundNumerous individual and environmental factors including diet may play an important role in the pathophysiology of irritable bowel syndrome (IBS). It is unclear to what degree dietary intake is affected in individuals with IBS. We aimed to perform a systematic review and meta‐analysis to summarize dietary intake of adults with IBS and to compare dietary intake between adults with IBS and non‐IBS controls.MethodsOvid MEDLINE, Embase, Cochrane, CINAHL, and Scopus were searched through February 2023 for clinical trials and observational studies measuring usual diet in adults with IBS. Pooled weighted averages were estimated for total energy, macronutrient, and micronutrient data. Mean differences (MD) in nutrient intake were estimated for adults with IBS versus non‐IBS controls using a random effects model. Heterogeneity was assessed by the inconsistency index (I2).Key ResultsSixty‐three full‐text articles were included in the review of which 29 studies included both IBS and control subjects. Nutrients not meeting the recommended intake level for any dietary reference values in the IBS population were fiber and vitamin D. Meta‐regression by female proportion was positively correlated with total fat intake and negatively correlated with carbohydrate intake. Comparisons between participants with IBS and controls showed significantly lower fiber intake in participants with IBS with high heterogeneity (MD: −1.8; 95% CI: −3.0, −0.6; I2 = 85%).Conclusions and InferencesThis review suggests that fiber and vitamin D intake is suboptimal in IBS; however, overall dietary intake does not appear to be comprised. Causes and consequences of reduced fiber in IBS deserve further study.Results of this systematic review and meta‐analysis suggest that fiber and vitamin D intake is suboptimal in IBS. However, overall intake of other macro‐ and micronutrients does not appear to be compromised. Causes and consequences of reduced fiber and Vitamin D intake in IBS deserve further study.

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Section: Resultsmentioning

confidence: 99%

“…Fat intake was analyzed from 19 studies 11,15,16,44,[48][49][50]54,56,62,63,69,87,89,90,[93][94][95][96][97][98][99][101][102][103][104] (N = 2369 participants with IBS, N = 5021 controls). There was no significant difference between participants with IBS and controls with moderate heterogeneity (MD: −2 g; 95% CI: −5.3, 1.2; I 2 = 59%).…”

Section: Total Fatmentioning

confidence: 99%

A systematic review and meta‐analysis of diet and nutrient intake in adults with irritable bowel syndrome

Veraza,

Calderon,

Jansson‐Knodell

et al. 2023

Neurogastroenterology Motil

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“…Furthermore, individuals with the highest amounts of vegetable intake were found to be 16% less likely to have a primary headache than others (OR: 0.84, 95% CI) ( 24 ). Another study ( n = 100) reported more frequent consumption of herbal beverages in individuals with migraine of moderate severity compared to those with severe migraine ( p = 0.014) ( 26 ). In a case-control study examining the oxidant/antioxidant balance and migraine characteristics ( n = 44), the total non-enzymatic antioxidant capacity was found to be reduced in chronic migraine patients and a negative and significant correlation was reported between the number of days with headaches in a month and the values of the following variables including catalase antioxidant enzymes ( r = −0.60, p < 0.001), superoxide dismutase ( r = −0.50, p < 0.001), and the Trolox equivalent antioxidant capacity ( r = −0.61, p < 0.001) ( 27 ).…”

Section: Discussionmentioning

confidence: 99%

Migraine severity, disability, and duration: Is a good diet quality, high intake of phytochemicals and polyphenols important?

et al. 2022

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ObjectivesDietary pattern may be the determinant of migraine prognosis through various mechanisms such as systemic inflammation, vasodilation, cerebral glucose metabolism, and mitochondrial dysfunction.This study was conducted to examine the relationship of the symptoms and signs of migraine with dietary polyphenols and the phytochemical intake and the quality of the diet.Materials and methodsIndividuals (n = 90), who were admitted to the headache outpatient clinic due to the diagnosis of episodic migraine, underwent physical examination by a neurologist. Migraine characteristics were assessed using the Migraine Disability Assessment Questionnaire and the Visual Analogue Scale. The Healthy Eating Index-2015 (HEI-2015) was used to evaluate the diet quality of individuals, and the Phytochemical Index developed by McCarty was used to determine the dietary intake of phytochemicals. Phenol-Explorer version 3.6 and the USDA Database for the Flavonoid Content of Selected Foods-Release 3.3 were used to calculate the dietary polyphenol intake.ResultsMigraine severity was negatively correlated with the intake of phytochemicals and good diet quality (r = −0.37, p = 0.0003; r = −0.37, p = 0.0003, respectively), and with the intake of phenolic components flavanones (r = −0.27, p = 0.01) and lignans (r = −0.27, p = 0.01). With respect to the food groups; migraine severity was found to be inversely correlated with the total phenol intake from olive oil, oil, and fruits (r = −0.26, p = 0.01; r = −0.21, p = 0.04; r = −0.24, p = 0.02, respectively), and the flavonoid intake from olive oil, oil, fruits, and vegetables (r = −0.26, p = 0.01; r = −0.26, p = 0.01; r = −0.35, p = 0.0007; r = −0.22, p = 0.04, respectively). Strikingly, fruit flavanone intake was correlated with low migraine severity (r = −0.39, p = 0.0002), and fruit flavanol intake was correlated with low migraine disability (r = −0.21, p = 0.04).ConclusionA high-quality diet rich in phytochemicals and polyphenols (especially flavanones and lignans) is associated with low migraine severity. Lower intake of phenols and flavonoids from vegetable oil, olive oil, fruits, and vegetables were associated with more severe migraine attacks. Examination of migraine characteristics and dietary pattern together with phytochemical and polyphenol intake may guide the development of dietary strategies to be used in migraine patients.

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“… 1 , 2 In addition to its own digestive tract symptoms, IBS is often merged by mental symptoms such as anxiety and depression, as well as physical symptoms such as migraine, fatigue, and sleeping disturbances. 3 - 5 A hospital in Bangladesh evaluated the incidence of mental illness among 110 IBS patients and revealed that the most common dysthymic disorder was anxiety (22.7%), followed by major depression (19.1%) and somatization disorder (14.5%). 6 The clinical manifestations of each individual are quite different, and some patients' mental symptoms are even more serious than those of gastrointestinal, which brings great difficulties to treatment and makes the patient's condition protracted.…”

Section: Introductionmentioning

confidence: 99%

Research Progress of Central and Peripheral Corticotropin-Releasing Hormone in Irritable Bowel Syndrome with Comorbid Dysthymic Disorders

et al. 2023

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Irritable bowel syndrome (IBS) is considered a stress disorder characterized by psychological and gastrointestinal dysfunction. IBS patients not only suffer from intestinal symptoms such as abdominal pain, diarrhea, or constipation but also, experience dysthymic disorders such as anxiety and depression. Studies have found that corticotropin-releasing hormone plays a key role in IBS with comorbid dysthymic disorders. Next, we will summarize the effects of corticotropin-releasing hormone from the central nervous system and periphery on IBS with comorbid dysthymic disorders and relevant treatments based on published literatures in recent years.

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The potential impact of nutritional intake on symptoms severity in patients with comorbid migraine and irritable bowel syndrome

Cited by 6 publications

References 35 publications

A systematic review and meta‐analysis of diet and nutrient intake in adults with irritable bowel syndrome

A systematic review and meta‐analysis of diet and nutrient intake in adults with irritable bowel syndrome

Migraine severity, disability, and duration: Is a good diet quality, high intake of phytochemicals and polyphenols important?

Research Progress of Central and Peripheral Corticotropin-Releasing Hormone in Irritable Bowel Syndrome with Comorbid Dysthymic Disorders

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