The post mortem temperature plateau and its role in the estimation of time of death. A review

Smart, Jimmy L.; Kaliszan, Michał

doi:10.1016/j.legalmed.2011.11.002

Cited by 38 publications

(21 citation statements)

References 33 publications

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“…For example, a smaller body size tends to cool faster than a larger one due to its higher total surface area to volume ratio (Lee 2009;Shkrum & Ramsay 2007). In addition, an obese person can retain body temperature for a much longer time as compared to a slim person due to the difference of body fat content (Smart & Kaliszan 2012;Wardak & Cina 2011). Aside from that, there are some ante mortem conditions, which may lead to abnormally high or low body temperature.…”

Section: Early Post Mortem Changesmentioning

confidence: 99%

“…Aside from that, there are some ante mortem conditions, which may lead to abnormally high or low body temperature. Condition associated with heat stroke, fever, stress, hyperthyroidism, brain injury, malignant hyperthermia, neuroleptic medication, sepsis, presence of toxins or drugs, ante mortem physical activity and age of deceased or certain causes of death (such as suffocation) will lead to abnormal initial body temperature (Adams 2009b;Smart & Kaliszan 2012).…”

Section: Early Post Mortem Changesmentioning

confidence: 99%

See 1 more Smart Citation

Decomposition Process and Post Mortem Changes: Review

Teo¹,

Hamzah²,

Hing³

et al. 2014

JSM

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Section: Early Post Mortem Changesmentioning

confidence: 99%

Section: Early Post Mortem Changesmentioning

confidence: 99%

Decomposition Process and Post Mortem Changes: Review

Teo¹,

Hamzah²,

Hing³

et al. 2014

JSM

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show abstract

“…A wide spectrum of methods has been developed and tested to estimate the time of death. For example, several physical, pathophysiological, biochemical, and microbiological processes occurring during the postmortem period have been proposed for PMI estimation (Henssge and Madea, 2007; Smart and Kaliszan, 2012). However, these assessment methods are still largely unreliable and inaccurate because of their susceptibility to environmental factors as well as large variations that exist among individuals.…”

Section: Introductionmentioning

confidence: 99%

Cell Death-Associated Ribosomal RNA Cleavage in Postmortem Tissues and Its Forensic Applications

Kim

Kyeong

et al. 2017

Molecules and Cells

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Estimation of postmortem interval (PMI) is a key issue in the field of forensic pathology. With the availability of quantitative analysis of RNA levels in postmortem tissues, several studies have assessed the postmortem degradation of constitutively expressed RNA species to estimate PMI. However, conventional RNA quantification as well as biochemical and physiological changes employed thus far have limitations related to standardization or normalization. The present study focuses on an interesting feature of the subdomains of certain RNA species, in which they are site-specifically cleaved during apoptotic cell death. We found that the D8 divergent domain of ribosomal RNA (rRNA) bearing cell death-related cleavage sites was rapidly removed during postmortem RNA degradation. In contrast to the fragile domain, the 5′ terminal region of 28S rRNA was remarkably stable during the postmortem period. Importantly, the differences in the degradation rates between the two domains in mammalian 28S rRNA were highly proportional to increasing PMI with a significant linear correlation observed in mice as well as human autopsy tissues. In conclusion, we demonstrate that comparison of the degradation rates between domains of a single RNA species provides quantitative information on postmortem degradation states, which can be applied for the estimation of PMI.

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“…There are many methods for estimating the time of death, which can be divided into two categories (rate methods and concurrence methods). In rate methods, which are mainly used in forensic practice, the time of death is estimated on the basis of postmortem changes, such as the amount and distribution of rigor mortis (Anders et al 2013, Bendall & Lawrie 1962, the change in body temperature (Smart & Kaliszan 2012, Al-Alousi et al, 2001 hypostasis (Honjyo et al, 2005), changes of potassium concentration in vitreous humor (Júnior et al, 2014), synovial fluid (Siddhamsetty et al 2014), pericardial fluid (Palmiere & Mangin, 2015) development and growth of insects in the corpse (Mohr & Tomberlin 2014) and the degree of putrefaction of the body (Buchan & Anderson, 2001).…”

Section: Introductionmentioning

confidence: 99%

Estimation of Postmortem Interval from Cartilage Changes of Rabbit Auricle

Paulis

Hassan

Abd-Elgaber

2016

Ain Shams Journal of Forensic Medicine and Clinical Toxicology

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In forensic practice, estimating the time of death is one of the most important procedures but is often extremely difficult. There are many methods for estimating the time of death, which can be divided into two categories (rate methods and concurrence methods). Postmortem decompositional changes to auricular cartilage were analyzed to help establish a new methodology in determining the postmortem interval. Methods: The ears were collected from rabbits buried in simulated shallow graves for different time periods (0, 5, 10, 15, 20, 25, 30 days). The auricles were examined both macroscopically and microscopically to detect changes occurring over a specified time. Results: Numerous macroscopic changes including color and texture changes and gradual degradation of cartilage were observed. LM showed gradual structural changes in the tissue over time including: cartilage matrix density and nuclear material. Conclusion: Postmortem degradation of ear cartilage may be useful for estimating a presumptive postmortem interval.

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The post mortem temperature plateau and its role in the estimation of time of death. A review

Cited by 38 publications

References 33 publications

Decomposition Process and Post Mortem Changes: Review

Decomposition Process and Post Mortem Changes: Review

Cell Death-Associated Ribosomal RNA Cleavage in Postmortem Tissues and Its Forensic Applications

Estimation of Postmortem Interval from Cartilage Changes of Rabbit Auricle

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