The possible role of particulate matter on the respiratory microbiome: evidence from in vivo to clinical studies

Relationship between Airway Microbiome and the Immune Response to Diesel Exhaust: A Randomized Crossover Controlled Exposure Study

“…Nevertheless, given that, to our knowledge, this is the first study in humans to experimentally connect assessment of the relationship between pollution exposure, the airway microbiome, and host immune response; our novel work adds to the growing body of investigations defining the roles that microbiota play in the natural history of chronic respiratory diseases. 8 – 10 An improved understanding of the mechanisms by which the microbiome interacts with the host and environment could empower patients to manage chronic respiratory illnesses and pave the path to developing novel therapeutic strategies.…”