The possible relation between stigma, parent psychiatric symptoms, quality of life and the disease burden in families of children with autism spectrum disorder in Egypt: a multicentre study

Gabra, Romany H.; Hashem, Doaa F.; Ahmed, Gellan K.

doi:10.1186/s41983-021-00426-w

Cited by 6 publications

(3 citation statements)

References 60 publications

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“…The previous literature corroborates this claim, as a similar trend occurred following a research work carried out in India where there was a negative correlation across all domains of QoL metrics with depression [34]. Additionally, an Egyptian-based study discovered significant links between lower quality-of-life scores experienced by parents and their anxiety [35]. Parents' quality of life positively and significantly correlated with their socioeconomic status.…”

Section: Discussionsupporting

confidence: 71%

Raising Hopes, Facing Challenges: Understanding Parental Well-Being in the Midst of Autism in Saudi Arabia

Alenezi,

Alsewailem,

Almubaddil

et al. 2024

Behavioral Sciences

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Background: This study aimed to investigate the levels of anxiety, depression, and quality of life among parents of children with autism spectrum disorder. It also compared the difference in these levels between mothers and fathers. Additionally, it quantifies the association between parental anxiety, depression, and quality of life, with various sociodemographic factors. Methods: This analytical, cross-sectional study was carried out between June and December 2022. An online questionnaire was completed by a sample of 394 parents of children with ASD (autism spectrum disorder) residing in Saudi Arabia. Three scales were used to assess depression, anxiety, and quality of life (QoL), respectively: Patient Health Questionnaire 9 (PHQ-9), Generalized Anxiety Disorder 7 (GAD-7), and World Health Organization Quality of Life—Brief Version (WHOQOL-BREF). Results: Most parents (70.8%) were mothers with an average age of 39 years, typically ranging from 30 to 48 years. Parents’ overall quality of life was 57.72 out of 100, indicating moderate satisfaction. Anxiety levels showed that 32% had mild, 17.8% moderate, and 14.7% severe anxiety. Similarly, depression levels revealed that 34.5% had minimal, 32.2% mild, and 18% moderate depression. Higher anxiety and depression scores were linked to a lower perceived QoL (quality of life). Moreover, the socioeconomic status index (SESi) was significantly and positively correlated with higher depression and lower quality of life. Conclusions: Autism Spectrum Disorder imposes a strain on parents of the autistic child. The responsibilities linked to the disability amplify the occurrence of depression and anxiety among parents, leading to a diminished quality of life.

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Section: Discussionsupporting

confidence: 71%

Raising Hopes, Facing Challenges: Understanding Parental Well-Being in the Midst of Autism in Saudi Arabia

Alenezi,

Alsewailem,

Almubaddil

et al. 2024

Behavioral Sciences

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“…The earlier rate, in 2018, was 1 in 59. An increase in ASD prevalence is visible CDC ., [12] Care givers for autistic children were found to have a low level of knowledge about the disease. Because of the inadequate parents knowledge this have an impact of the parent practices and attitude toward their children with autism Mousa et al, [27].…”

Section: Introductionmentioning

confidence: 99%

Assessment of knowledge,attitude and practices of parents having children with autism

Elhawat

2023

Helwan International Journal for Nursing Research and Practice

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Autism Disorder is a developmental disorder usually noticed among children within the first two or three years of their lives which have a profound impairment in social communication and social interaction and restricted and repetitive behavior. The study was aimed to: Assess knowledge, attitude and practices of parents having children with autism Design: A descriptive research design was utilized. Setting: the study was carried out in outpatient clinic of autism at Al-Abbassia hospital for mental health and addiction and Helwan hospital for psychiatric and mental health. Subjects: the study sample was 60 parents of children of children diagnosed with autism from both sexes. Tools: data was collected by using four tools; Tool (1)socio-demographic questionnaire for the characteristic of the children and their parents, Tool (2) parent's knowledge scale regarding autism disorder andTool (3) Attitude scale of parents toward their children with autism, parents, Tool (4) practices scale regarding caring of children with autism. Results: the study results showed that. Nearly more than three quarters of the parents had unsatisfactory knowledge regarding their children disorder. Slightly more than three quarters of the parents had incompetent practices regarding their children with autism. Conclusion:the present study concluded that,more than three quarters of the parent had unsatisfactory knowledge and in competent practices regarding caring of their children. Also, there was statistically significant difference between total knowledge score and the parent's socio demographic characteristics. In addition to, there was a highly statistically significant difference between total knowledge scoreand total practices score of having children with autism. Recommendation:Conducting a continuous practical training and health educational programs for all members of the families having children with autism.

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“…Moreover, an Egyptian study has associated an increased disease burden on families of ASD with stigma, parental health problems, as well as impaired quality of life. When one of these factors was present, the risk of the other factors would also increase [2].…”

Section: Introductionmentioning

confidence: 99%

Neuroinflammation in autism spectrum disorders: potential target for mesenchymal stem cell-based therapy

Wong

2022

Egypt J Neurol Psychiatry Neurosurg

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Background Autism spectrum disorders (ASD) include a group of neurodevelopmental disorders characterised by repetitive behaviours and impairments in communication, emotional and social skills. This review gives an overview of ASD, focusing on the aetiological and clinical aspects. It also discusses the role of neuroinflammation in ASD, critically examines the current evidence on the therapeutic effects of MSCs in ASD and consolidates key findings in this area of research. Results Many environmental and genetic factors have been linked to the aetiology of ASD. It has become increasingly evident that neuroinflammation plays a role in ASD. Conventional treatment of ASD revolves around psychosocial approaches whereas recent studies have turned to alternative approaches such as mesenchymal stem cell (MSC)-based therapy, owing to the well-recognised immunomodulatory characteristics of MSCs. Preclinical and clinical studies have shown that MSCs were able to exert anti-inflammatory effects and alleviate ASD symptoms. Conclusions There are many preclinical studies that support the use of MSCs in ASD. However, there are relatively fewer clinical studies concerning the safety and efficacy of MSCs in ASD, which warrants more large-scale clinical studies for future research.

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The possible relation between stigma, parent psychiatric symptoms, quality of life and the disease burden in families of children with autism spectrum disorder in Egypt: a multicentre study

Cited by 6 publications

References 60 publications

Raising Hopes, Facing Challenges: Understanding Parental Well-Being in the Midst of Autism in Saudi Arabia

Raising Hopes, Facing Challenges: Understanding Parental Well-Being in the Midst of Autism in Saudi Arabia

Assessment of knowledge,attitude and practices of parents having children with autism

Neuroinflammation in autism spectrum disorders: potential target for mesenchymal stem cell-based therapy

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