Abstract:Objective: To evaluate the potential protective effect of pumpkins’ seed extract on oxidative stress and cyclin D1 expression associated with mammary gland carcinoma in rats.
Design: Randomized controlled experimental study.
Animals: Forty female Sprague Dawley rats.
Procedures: Rats were allocated equally to four groups (10 rats each); group 1 (control group); group 2 received 7, 12 dimethylbenzanthracene (DMBA) subcutaneously in the mammary region to induce carcinoma. Group 3 received pumpkin seed extract a… Show more
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