The polymorphism of progesterone: Stabilization of a ‘disappearing’ polymorph by co‐crystallization

Ammonolysis-based microencapsulation technique using isopropyl formate as dispersed solvent

“…6 shows the DSC thermograms of progesterone, blank microspheres, and those with different payloads of progesterone. In accordance with literature, progesterone exists in two major polymorphic forms of ␣ (bp = 129-131 • C) and ␤ (bp = 121-123 • C) (Lancaster et al, 2007). In our experiment progesterone showed a sharp endotherm at 129 • C, representing the melting point of ␣ form.…”

Characterization of progesterone loaded biodegradable blend polymeric nanoparticles

“…In figure 1 these bands are located at 1656 cm -1 and 1703 cm -1 respectively in progesterone spectra. The characteristic band of the double bond of progesterone is located between 850 and 900 cm -1 (LANCASTER et al, 2007). Progesterone band located at 870cm -1 is also found in figure 1.…”

Absorbing a Little Water: The Structural, Thermodynamic, and Kinetic Relationship between Pyrogallol and Its Tetarto-Hydrate

“…Since types A and B structures are alternative packing modes of the same stack of O–H···O C 1 1 (6) chains, this might result in the occurrence of type B stacking faults in the AH. Having energetically competitive modes of combining 2D sheets has accounted for polymorphism and/or stacking disorder in aspirin, 89 phloroglucinol dihydrate, 59 or modafinil 90 and may account for the occurrence of concomitant polymorphism 91 (e.g., aprepitant 92 and progesterone 93 ). Since the alternate type A packings (Figure S10 of the Supporting Information) could rearrange easily to the more stable experimental packing, this significantly reduces the possibility that these could be found as long-lived metastable anhydrate polymorphs.…”