The placenta as a barrier for toxic and essential elements in paired maternal and cord blood samples of South African delivering women

Rudge, Cibele Vieira Cunha; Röllin, Halina B.; Nogueira, Claudina; Thomassen, Yngvar; Rudge, Marilza Vieira Cunha; Odland, Jon Øyvind

doi:10.1039/b903805a

Cited by 167 publications

(98 citation statements)

References 51 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…When we compared our results with previous studies (8,14), we found the levels to be higher in pregnant women and the cord blood of the study group. Presence of these toxic metals in the meconium may indicate the excretion of the metals by the baby in utero.…”

Section: Discussionsupporting

confidence: 54%

“…In maternal blood the maximum amount of lead was seen in those mothers residing in Steel Town, Sadder Town and New Karachi Town. Overall, the number of towns with levels greater than 0.0088 (maternal blood) (14), 0.00032 (cord blood) (14) and meconium 12 ± 14.9 (18) was 11/20, i.e. 55% in each sample tested.…”

Section: Resultsmentioning

confidence: 99%

“…In Hyderabad, maternal blood contained cadmium, while surprisingly it was absent in the cord blood and meconium of the new-born. Overall, the percentage of towns with level greater than 0.0089 (maternal blood) (14), 0.00032 (cord blood) (14) and meconium 3.0 ± 7.44 (4) was 20%, 5% and 20% respectively, in each sample tested.…”

Section: μ/G Dry Wt Was Toxic (24) ^P-value Shows That In Gulbarg Tomentioning

confidence: 99%

“…In Korangi, Landhi, Lyari, Malir, North Nazimabad, Orangi and Site Town areas, zinc was present in the same amount both in cord blood and maternal blood. Overall, the percentage of towns with level greater than 0.883 ± 0.070 (maternal blood) (15), 4.738 (cord blood) (14) and meconium >100μg/g (8) was 90%, 75% and 55% respectively, in each sample tested.…”

Section: μ/G Dry Wt Was Toxic (24) ^P-value Shows That In Gulbarg Tomentioning

confidence: 99%

“…Methodology for the initial preparation of meconium for analysis was problematic as it is a thick viscous material (10,13). Quantitative analysis of heavy metals was done by flame atomic absorption spectrophotometer for meconium, at IAC, including the quantitative analysis performed by Inductive Coupled Plasma-Optical Emission Technique (ICP-OES) (14)(15)(16).…”

Section: Sampling Techniquementioning

confidence: 99%

See 4 more Smart Citations

Toxic metals in maternal blood,cord blood and meconium of newborn infants in Pakistan

Aziz

Ahmed

Karim

et al. 2017

East Mediterr Health J

View full text Add to dashboard Cite

Taux de métaux toxiques et d'éléments traces dans le sang maternel, le sang cordonal et le méconium des nouveau-nés au PakistanRÉSUMÉ Les métaux toxiques et la carence ou l'excès en éléments traces peuvent avoir des effets nocifs sur la santé. La présente étude avait pour objectif de quantifier les taux de métaux toxiques (plomb, cadmium) et d'éléments traces (zinc, cuivre, aluminium et fer) contenus dans le sang des femmes enceintes, le sang cordonal, et le méconium des nouveau-nés dans des zones industrielles de Karachi (Pakistan). Une recherche analytique a été menée en 2011 et 2012 sur des femmes enceintes et des nouveau-nés au niveau socioéconomique faible dans vingt villes proches des zones industrielles de Sindh, de Federal B et de Korangi à Karachi, où une pollution environnementale avait été anticipée. Les échantillons de sang des femmes enceintes (n = 416), de sang cordonal (n = 309) et de méconium (n = 309) ont fait l'objet d'une analyse quantitative à la recherche de métaux et d'éléments traces. Les résultats ont indiqué que les mères résidant dans des villes sidérurgiques présentaient les taux de plomb les plus élevés. Le méconium contenait des concentrations élevées de métaux lourds toxiques et d'éléments traces par rapport au sang cordonal et au sang maternel. Les métaux toxiques contenus dans le sang maternel étaient présents en grandes quantités. Par conséquent, des mesures de sécurité devraient être prises lorsque les déchets industriels sont éliminés afin de prévenir la contamination de la population. and meconium (n = 309) were analyzed quantitatively for metals and trace elements. Results indicated that mothers residing in steel towns were found to have the highest levels of lead. Meconium contained high levels of toxic heavy metals and trace elements compared to cord blood and maternal blood. Maternal blood toxic metals were present in high quantities. Therefore, safety measures should be taken when industrial waste is disposed of in order to prevent population contamination. ‫باكستان‬ ‫يف‬ ‫الوالدة‬ ‫حديثي‬ ‫ّي‬ ‫وعق‬ ‫الرسي‬ ‫احلبل‬ ‫ودم‬ ‫األمهات‬ ‫دم‬ ‫يف‬ ‫الشحيحة‬ ‫والعنارص‬ ‫ة‬

show abstract

Section: Discussionsupporting

confidence: 54%

Section: Resultsmentioning

confidence: 99%

Section: μ/G Dry Wt Was Toxic (24) ^P-value Shows That In Gulbarg Tomentioning

confidence: 99%

Section: μ/G Dry Wt Was Toxic (24) ^P-value Shows That In Gulbarg Tomentioning

confidence: 99%

Section: Sampling Techniquementioning

confidence: 99%

See 3 more Smart Citations

Toxic metals in maternal blood,cord blood and meconium of newborn infants in Pakistan

Aziz

Ahmed

Karim

et al. 2017

East Mediterr Health J

View full text Add to dashboard Cite

show abstract

Endocrine Disruptors: Genetic, Epigenetic, and Related Pathways

Ansari

Alfuraih

Shekh³

et al. 2023

Impact of Engineered Nanomaterials in Genomics and Epigenomics

View full text Add to dashboard Cite

Prenatal exposure to selenium may protect against wheezing in children by the age of 3

Baïz

Chastang

Ibáñez

et al. 2016

Immunity Inflam & Disease

View full text Add to dashboard Cite

IntroductionIt has been suggested that human in utero exposure to heavy metals such as selenium can reduce the prevalence of childhood asthma and allergic diseases. However, data on this topic are scarce. The objective of the present study was to assess the putative associations between maternal selenium level during pregnancy and the risk of asthma, wheezing, allergic rhinitis, and atopic dermatitis in children from the EDEN birth cohort by the age of 1 and 3 years.MethodsPlasma selenium concentrations were measured in maternal blood during mid‐pregnancy (24–28 weeks of gestation) in 861 mothers. Cohort children were followed up from birth to 3 years using health questionnaires filled out by the parents for asthma, wheezing, allergic rhinitis, and atopic dermatitis. Maternal plasma selenium was related to the childhood outcomes by the age of 1 and 3 years.ResultsOur results showed a significant negative association between a high maternal plasma selenium level during pregnancy and the risk of wheezing in the child by the age of 1 and 3 years. However, maternal plasma selenium during pregnancy was not associated with the prevalence of asthma, allergic rhinitis or atopic dermatitis.ConclusionsThe results of this study suggest that the level of fetal exposure to maternal selenium could have an influence on the risk of wheezing in infancy and potentially on the risk of developing asthma later in life.

show abstract

The placenta as a barrier for toxic and essential elements in paired maternal and cord blood samples of South African delivering women

Cited by 167 publications

References 51 publications

Toxic metals in maternal blood,cord blood and meconium of newborn infants in Pakistan

Toxic metals in maternal blood,cord blood and meconium of newborn infants in Pakistan

Endocrine Disruptors: Genetic, Epigenetic, and Related Pathways

Prenatal exposure to selenium may protect against wheezing in children by the age of 3

Contact Info

Product

Resources

About