The phytochemistry and medicinal value of Psidium guajava (guava)

Abstract

Psidium guajava (guava) is well known tropic tree which is abundantly grown for fruit. Many countries have a long history of using guava for medicinal purposes. This plant finds applications for the treatment of diarrhea, dysentery, gastroenteritis, hypertension, diabetes, caries and pain relief and for improvement in locomotors coordination. Its leaf's extract is being used as a medicine in cough, diarrhea, and oral ulcers and in some swollen gums wound. Its fruit is rich in vitamins A, C, iron, phosphorus and calcium and minerals. It contains high content of organic and inorganic compounds like secondary metabolites e.g. antioxidants, polyphenols, antiviral compounds, anti-inflammatory compounds. The phenolic compounds in guava help to cure cancerous cells and prevent skin aging before time. The presence of terpenes, caryophyllene oxide and p-selinene produces relaxation effects. Guava leaves contain many compounds which act as fungistatic and bacteriostatic agents. Guava has a high content of important antioxidants and has radio-protective ability. Quercetin is considered as most active antioxidant in the guava leaves and is responsible for its spasmolytic activity. Its ethyl acetate extract can stop the germ infection and thymus production. Guava possesses anti-viral, anti-inflammatory, anti-plaque and anti-mutagenic activities. Guava extract shows antinociceptive activity and is also effective in liver damage inflammation and serum production. Ethanolic extract of guava can increase the sperm quality as well as quantity and can be used for the treatment of infertile males.

A BIOPROCESS DEVELOPMENT STUDY OF POLYPHENOL PROFILE, ANTIOXIDANT AND ANTIMICROBIAL ACTIVITIES OF KOMBUCHA ENRICHED WITH Psidium guajava L.

“…It is interesting to note, that the extended fermentation period will encourage the phenolic material and the antioxidant operate but will not raise the acidic flavour. Owing to greater antioxidant action and elevated prospective safety advantages, 12 days of fermentation are proposed not more as the reduction of both the phenolic content and that of the antioxidant action and the microbial population for kombucha tea used with the substrate have been noted (Muhialdin et al, 2019). acetic acid and catechins have been well informed about the potential to inhibit a range of gram-positive and gram-negative microorganisms (Jayabalan et al, 2014).…”

In vitro antibacterial activity of Psidium guajava (Guava) leaves extract on carbapenem-resistant Klebsiella pneumoniae causing multi-drug resistant systemic infections

“…Psidium guajava (guava) is known for its fruit and medicinal purposes in the tropical countries. Guava is indicated for the treatment of gastroenteritis, caries, diarrhea, dysentery, diabetes, hypertension and pain relief (Naseer et al, 2018). It contains high content of organic and inorganic compounds such as antimicrobials, antioxidants, polyphenols and anti-inflammatory compounds (Naseer et al, 2018).…”

Presence of phytochemicals in fruits and leaves of guava (Psidium guajava Linn.) for cancer prevention: A mini review

“…is a medicinal plant belonging the family Myrtaceae and found in the many places of India. The leaves and fruits are used for the traditional medicine worldwide [1][2][3][4] . In India, the fruits are edible food crop as low cost compared to other fruits and poor people can also afford as food 3,5 .…”

“…tannins, phenols, triterpenes, βavonoids, essential oils, saponins, carotenoids, lectins, vitamins, fibre and fatty acids [5][6][7][8][9][10] that prevent several diseases such as digestive disorders, cancers and mutations, bacterial infection, menstrual disorders, dermatitis, neurodegenerative disease, diabetes, lung problems, free radical generation, etc. [4][5][6][11][12][13] .…”

“…The combination studies as extraction and characterization of phytocompounds of guava fruits and leaves as well as experiments on animal models with these extracts are rare [22][23] . Major review works were observed on the disease prevention by using extracts of different parts of guava tree 2,4,19,24 .…”