The Physiology of Peritoneal Solute, Water, and Lymphatic Transport

Krediet, Raymond T.

doi:10.1007/978-0-387-78940-8_6

Cited by 13 publications

(19 citation statements)

References 263 publications

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“…Serum ionized calcium levels must be closely monitored when the dialysate contains a high concentration of bicarbonate to prevent the risk of tetany. It should also be noted that bicarbonate loss from dialysate is increased in association with high ultrafiltration rates as a result of convective clearance (94).…”

Section: Pediatric Guidelinesmentioning

confidence: 99%

Peritoneal Dialysis for Acute Kidney Injury

et al. 2014

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Section: Pediatric Guidelinesmentioning

confidence: 99%

Peritoneal Dialysis for Acute Kidney Injury

et al. 2014

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“…Peritoneal transport of low molecular weight solutes (such as urea and creatinine) occurs by diffusion and convection through small pores, at the level of inter-endothelial clefts, while transport of macromolecules is predicted to occur across large pores [3,24]. The identity of these large pores has not been established, even if some structures have been postulated, including plasmalemma vesicles, vesicular-vacuolar organelles, large interendothelial clefts or venular interendothelial gaps [3].…”

Section: Peritoneal Solute Transport: Impact Of Local Intraperitonealmentioning

confidence: 99%

“…The identity of these large pores has not been established, even if some structures have been postulated, including plasmalemma vesicles, vesicular-vacuolar organelles, large interendothelial clefts or venular interendothelial gaps [3].…”

Section: Peritoneal Solute Transport: Impact Of Local Intraperitonealmentioning

confidence: 99%

“…According to Fick's principles, peritoneal solute transport rate (PSTR) is primarily determined by the number of perfused peritoneal capillaries in contact with the dialysis solution (the effective peritoneal surface area, EPSA), the intrinsic permeability of the membrane and the concentration gradient between blood and dialysate [3]. Data from large cohorts of peritoneal dialysis patients with peritoneal equilibration testing at the initiation of peritoneal dialysis indicate an important -more than two-fold -interindividual variability in the initial PSTR [25].…”

Section: Peritoneal Solute Transport: Impact Of Local Intraperitonealmentioning

confidence: 99%

“…The peritoneum can be viewed as a semi-permeable, heteroporous membrane containing three major components: a monolayer of mesothelial cells; an interstitial tissue consisting of bundles of collagen in a mucopolysaccharide hydrogel; and a dense network of capillaries [3] (Fig. 1a).…”

Section: Introductionmentioning

confidence: 99%

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Water and solute transport across the peritoneal membrane

Morelle

Devuyst

2015

Current Opinion in Nephrology and Hypertension

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Sp460correlation Between Ultrafiltration Coefficient (Lpa) and Effective Lymphatic Absorption Rate (Elar) in Chronic Ambulatory Peritoneal Dialysis Patients; A Shift of Paradigm?

Hekmat

2016

Nephrology Dialysis Transplantation

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Background:The relative contribution of transcapillary water movement and lymphatic reabsorption in peritoneal dialysis (PD) is a critical issue, particularly in patients with ultrafiltration failure (UFF). Based on routine results obtained from the PD Adequest 2.0 software, the present study aimed to re-evaluate the separate effects of transcapillary water movement and lymphatic reabsorption on the net ultrafiltration capacity in continuous ambulatory peritoneal dialysis (CAPD) patients without UFF. Methods:Seventy CAPD patients without UFF and PD duration less than 2 years entered the study. The study was conducted during January-April 2016 at Mashhad University of Medical Sciences, Mashhad, Iran. Each patient had 1 to 3 peritoneal equilibration test (PET) results which were used to analyze the determinants of fluid transport, lymphatic reabsorption, and ultrafiltration. Pearson and Spearman correlation tests were used to determine the correlation between continuous and ordinal factors, respectively. The data were analyzed using the SPSS software version 19.0. Results:In terms of the effective lymphatic absorption rate (ELAR) and ultrafiltration coefficient (LpA) values, there was no difference in the high or high-average transporters compared to the low or low-average transporters. However, a positive and highly significant correlation between ELAR and LpA was found. Conclusion: A significant correlation between ELAR and LpA was found in CAPD patients without UFF and duration less than 2 years from the beginning of PD. The abstract was presented in the 53rd ERA-EDTA Congress, Austria, as a poster and published in Nephrology Dialysis Transplantation as a supplement (2016; Vol. 31).

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The Physiology of Peritoneal Solute, Water, and Lymphatic Transport

Cited by 13 publications

References 263 publications

Peritoneal Dialysis for Acute Kidney Injury

Peritoneal Dialysis for Acute Kidney Injury

Water and solute transport across the peritoneal membrane

Sp460correlation Between Ultrafiltration Coefficient (Lpa) and Effective Lymphatic Absorption Rate (Elar) in Chronic Ambulatory Peritoneal Dialysis Patients; A Shift of Paradigm?

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