The Physiological Occlusion of the Central Canal May Be a Prerequisite for Syringomyelia Formation
Chuan Jiang,
Xinyu Wang,
Chunli Lu
et al.
Abstract:Objective: Syringomyelia is a common central nervous system disease characterized by the dilation of the central canal (CC). Regarding the pathogenesis of syringomyelia, cerebrospinal fluid (CSF) circulation obstruction in the subarachnoid space (SAS) of the spinal cord has been widely accepted. However, clinical and animal studies on obstructing the CSF in SAS failed to form syringomyelia, challenging the theory of SAS obstruction. The precise pathogenesis remains unknown.Methods: We utilized an extradural co… Show more
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