The photodisintegration of molybdenum

Gellie, R.W.; Lokan, K.H.

doi:10.1016/0029-5582(64)90668-6

Cited by 9 publications

(2 citation statements)

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“…99m Tc is a basic radioisotope used in nuclear medicine for diagnostics of the liver, lungs and bones. [5][6][7][8] The alternative accelerator-based production methods 9 of both 99 Mo and 99m Tc include 238 U photofission, 10 phototransmutation of 100 Mo via the 100 Mo(,n) 99 Mo channel 11 or the direct production of 99m Tc via the 100 Mo(p,2n) transformation. 12 99m Tc can be produced in small medical cyclotrons, as reveals from the theoretical studies, 13 and the IAEA recommendations.…”

Section: Introductionmentioning

confidence: 99%

Application of therapeutic linear accelerators for the production of radioisotopes used in nuclear medicine

Konefał

Orlef

Sokół

2022

Polish Journal of Medical Physics and Engineering

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This review paper summarizes the possibilities of the use of therapeutic linear electron accelerators for the production of radioisotopes for nuclear medicine. This work is based on our published results and the thematically similar papers by other authors, directly related to five medical radioisotopes as 99Mo/99mTc, 198Au, 186Re, 188Re, 117mSn, produced using therapeutic linacs. Our unpublished data relating to the issues discussed have also been used here. In the experiments, two types of radiation were included in the analysis of the radioisotope production process, i.e. the therapeutic twenty-megavolt (20 MV) X-rays generated by Varian linacs and neutron radiation contaminating the therapeutic beam. Thus, the debated radioisotopes are produced in the photonuclear reactions and in the neutron ones. Linear therapeutic accelerators do not allow the production of radioisotopes with high specific activities, but the massive targets can be used instead. Thus, the amount of the produced radioisotopes may be increased. Apart from linear accelerators, more and more often, the production of radioisotopes is carried out in small medical cyclotrons. More such cyclotrons are developed, built, and sold commercially than for scientific research. The radioisotopes produced with the use of therapeutic linacs or cyclotrons can be successfully applied in various laboratory tests and in research.

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Section: Introductionmentioning

confidence: 99%

Application of therapeutic linear accelerators for the production of radioisotopes used in nuclear medicine

Konefał

Orlef

Sokół

2022

Polish Journal of Medical Physics and Engineering

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“…Reactor method of 98 Mo thermal neutron irradiation produces low specific activity 99 Mo through the 98 Mo (n,γ) 99 Mo transformation [4]. Accelerator-based production of 99 Mo, through the 235 U (γ,f) 99 Mo and 100 Mo (γ,n) 99 Mo reactions [5, 6] was recently elaborated and these methods make it possible to obtain high activity 99 Mo. Currently, due to the large number of cyclotrons in the world, the most promising method is irradiation of enriched 100 Mo by protons in the 100 Mo (p,2n) 99m Tc reaction.…”

Section: Introductionmentioning

confidence: 99%

New precipitation method for isolation of 99mTc from irradiated 100Mo target

Gumiela

Dudek

Bilewicz

2016

J Radioanal Nucl Chem

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Technetium-99m is the most widely used radionuclide in nuclear medicine. This work describes the method to separate 99mTc from irradiated 100Mo target. For this purpose we utilized formation of ammonium molybdenum phosphate (AMP) and have optimized the four parameters of the process. The proposed process is promising and allows fast separation of macroamounts of molybdenum without co-precipitation of 99mTc. The concentration of molybdenum in solution after precipitation of AMP was lower than 300 µg ml−1. Additional purification using AnaLigTc-02 is required to obtain solution with lower concentration of molybdenum.

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