The Personality Disorder Examination: A Preliminary Report

Loranger, Armand W.; Susman, Virginia L.; Oldham, John M.; Russakoff, L. Mark

doi:10.1521/pedi.1987.1.1.1

Cited by 299 publications

(140 citation statements)

References 2 publications

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“…Parts of the International Personality Disorder Examination [34] were applied for axis II diagnoses. In addition, an unstructured psychiatric interview and a family history evaluation were completed for each subject.…”

Section: Diagnostic Proceduresmentioning

confidence: 99%

Genome Scan for Susceptibility Loci for Schizophrenia

Bailer¹,

Leisch

Meszaros³

et al. 2000

Neuropsychobiology

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Objective: Schizophrenia is a relatively common, often chronic and debilitating mental illness. Evidence from various studies has clearly demonstrated that genetic factors contribute substantially to the etiology. The goal of this study was to identify chromosomal regions likely to contain schizophrenia susceptibility genes. Methods: A genome-wide map of 388 microsatellite DNA markers was genotyped in 5 schizophrenia families. Nonparametric linkage analysis (Genehunter) was used to assess the pattern of allele sharing at each marker locus relative to the presence of disease. Results: Nonparametric linkage scores did not reach a genome-wide level of statistical significance (p < 0.00002) or a p value suggestive of linkage (p < 0.007) for any marker; however, one p value suggested replicated linkage (p < 0.01) at chromosome 6p24 in region D6S309 (p = 0.0047). Furthermore, 11 markers resulted in p < 0.05 at chromosomes 6p, 6q, 10q, 12q and 14q. Conclusions: Despite the differences in diagnostic schemes, in markers used and methods of analyses between studies published so far, we think that our result supports the notion that there is possibly some consistent evidence for replicated linkage of a schizophrenia susceptibility locus around the region of D6S309 at chromosome 6p24.

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Section: Diagnostic Proceduresmentioning

confidence: 99%

Genome Scan for Susceptibility Loci for Schizophrenia

Bailer¹,

Leisch

Meszaros³

et al. 2000

Neuropsychobiology

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show abstract

“…Axis II assessments were made by direct interviews using the Personality Disorder Examination (PDE; Loranger, Susman, Oldham, & Russakoff, 1987). The PDE is a standardized, semi-structured clinical interview assessing DSM-III-R personality disorders.…”

Section: Subjects and Assessment Approachmentioning

confidence: 99%

“…The PDE developers (Loranger et al, 1987) reported reliabilities of the instrument for schizotypal, histrionic, borderline, antisocial and compulsive disorders of . 80, .77, .96, .70, and .88, respectively.…”

Section: Subjects and Assessment Approachmentioning

confidence: 99%

Personality features and disorder in the subjects in the New York high-risk project

Squires-Wheeler¹,

Skodol²,

Adamo³

et al. 1993

Journal of Psychiatric Research

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SummaryOne hundred and seventy-five offspring of parents in two psychiatrically ill groups and of normal controls in the New York High-Risk Project (NYHRP) were assessed for Axis II personality traits and disorders as defined by the Diagnostic and Statistical Manual of Mental Disorders, Third Edition, Revised (DSM-III-R). These offspring include: subjects at high risk for schizophrenia (HRSz, n = 48), all of whom have a parent with schizophrenic disorder; subjects at high risk for affective disorder (HRAff, n = 40), all of whom have a parent with affective disorder; and subjects at no increased risk for psychiatric illness (NC, n = 87), whose parents are psychiatrically normal.The trained interviewers, who administered a standardized direct interview, were blind to parental clinical status and to previous clinical status of the offspring.The rates for any personality disorder (PD) ranged from 7% to 20%. Comorbidity between Axis I and Axis II disorders was high for all groups.

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“…We recently reported a three-factor solution for the DSM-III-R criteria for borderline personality disorder (9), using ratings obtained from the Personality Disorder Examination (15) in an acutely ill impatient study group. The first factor, labeled "disturbed relatedness," consisted of the following criteria: unstable relationships (DSM-III-R criterion number 1), identity disturbance (number 6), and chronic feelings of emptiness (number 7).…”

mentioning

confidence: 99%

Confirmatory Factor Analysis of DSM-IV Criteria for Borderline Personality Disorder: Findings From the Collaborative Longitudinal Personality Disorders Study

Sanislow¹,

Grilo²,

Morey³

et al. 2002

AJP

273

172

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Objective: This study tested the factor structure of the DSM-IV criteria for borderline personality disorder by using confirmatory methods for the analysis of covariance structures in a large group from a multisite study.Method: A total of 668 primarily treatment-seeking subjects were reliably assessed for personality disorders by using the Diagnostic Interview for DSM-IV Personality Disorders. Associations among criteria for borderline personality disorder were examined. A confirmatory factor analysis was performed to test diagnosis as a unitary construct and to test an earlier-reported three-factor model comprising disturbed relatedness, behavioral dysregulation, and affective dysregulation. The three-factor model was subsequently tested by using a subset (N=498) of the study group that was reassessed 2 years later by independent evaluators who were blind to original diagnoses. Results:Internal consistency of the borderline personality disorder diagnosis was adequate for both baseline and follow-up assessments. A confirmatory factor analysis model testing the borderline personality disorder diagnosis as a unitary construct provided good fit, and the threefactor model offered a significantly better fit for the baseline assessment. The threefactor model was replicated with the 2-year follow-up data. Conclusions:The diagnostic criteria for borderline personality disorder appear to reflect a statistically coherent construct. Three homogeneous components were supported empirically, lending conceptual clarity to different classes of the criteria for borderline personality disorder.

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The Personality Disorder Examination: A Preliminary Report

Cited by 299 publications

References 2 publications

Genome Scan for Susceptibility Loci for Schizophrenia

Genome Scan for Susceptibility Loci for Schizophrenia

Personality features and disorder in the subjects in the New York high-risk project

Confirmatory Factor Analysis of DSM-IV Criteria for Borderline Personality Disorder: Findings From the Collaborative Longitudinal Personality Disorders Study

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