The Persistence of HIV-Associated Neurocognitive Disorder (HAND) in the Era of Combined Antiretroviral Therapy (cART)

Singer, Elyse J.; Nemanim, Natasha

doi:10.1007/978-1-4939-7290-6_16

Cited by 2 publications

(6 citation statements)

References 225 publications

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“…However, the milder forms of HIV-associated neuro-cognitive disorders are not as effectively impacted by treatment (Fazeli et al 2014). This is thought to be because concentrations of ART in the brain are at lower levels than in the blood (Singer and Nemanim 2017). The most likely explanation for most cognitive decline in long-term survivors is the interaction between HIV and the neurological impacts of normal ageing (Brew 2010).…”

Section: Physical Health Experiences Of Ageing With Hivmentioning

confidence: 99%

“…The impact of neurological decline on functioning is an emerging concern (Alford et al 2019;Singer and Nemanim 2017). Cognitive decline means a person is drawing on fewer cognitive resources to cope and the ability to develop solutions to problems that arise is impaired (Vance 2010).…”

Section: Physical Health Experiences Of Ageing With Hivmentioning

confidence: 99%

“…Cognitive decline means a person is drawing on fewer cognitive resources to cope and the ability to develop solutions to problems that arise is impaired (Vance 2010). Neurological decline could have a few different isolated or synergistic causes (Singer and Nemanim 2017;Clifford et al 2017). The CIPHER Study Group working in the European region cautioned that the cause of cognitive decline in PLHIV was difficult to pinpoint as it coincides with self-reported struggles with activities of daily living arising from a range of psychosocial hardships including poverty, anxiety and depression (Laverick et al 2017).…”

Section: Physical Health Experiences Of Ageing With Hivmentioning

confidence: 99%

“…Of particular concern to participants when contemplating 'where will I end up?' (Rory, E3, T1) was the effect of HIV on cognitive functioning despite a sustained undetectable viral load (Singer and Nemanim 2017). Marshall (E2, T2) called this 'CRAFTS, Can't Remember a Flaming Thing'.…”

Section: 'Can't Remember a Flaming Thing': Cognitive Declinementioning

confidence: 99%

“…Given the uncertainties of living with HIV and being on guard to protect against stigma and discrimination, participants often had to actively manage their stress levels to not be overwhelmed. Stress and anxiety can negatively impact cognition (Vance et al 2012;Singer and Nemanim 2017;Clifford et al 2017), and this highlights the importance of mental health being proactively addressed as a part of primary health care provision, rather than relying on expensive specialist interventions.…”

Section: I've Already Realised I've Got To Start Getting Back Into Volunteering Ormentioning

confidence: 99%

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Ageing with HIV: a qualitative longitudinal study of the lived experience of older homosexual men in regional Queensland

Gardiner¹

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Kate Rears provided 13 hours of professional editing services, primarily proof reading of the thesis post-examination to ensure consistency.Chris Howard who worked for Positive Directions and then Queensland Positive People was a particularly active and insightful collaborator throughout the study.Throughout this journey, Charoensak Srikanchana, my partner of 23 years, provided unfailing support, kindness and enthusiasm, as well as practical support such as delicious meals for interview teams in the field.

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Section: Physical Health Experiences Of Ageing With Hivmentioning

confidence: 99%