Aim: To evaluate the outcomes of an apically repositioned flap (ARF) plus xenogeneic collagen matrix (XCM) in augmenting keratinized mucosa width (KMW) around dental implants when compared with ARF plus free gingival grafts (FGG).Materials and methods: Twenty-six participants with at least one site with KMW ≤2 mm were randomized into FGG or XCM group. Clinical examinations were performed at baseline and at 2 and 6 months after surgery, including KMW, keratinized mucosa thickness, gingival index (GI), and probing depth (PD). Post-operative pain and patient satisfaction were also evaluated.Results: At 6 months, FGG attained a greater increase of KMW and thicker mucosa than XCM (4.1 ± 1.6 mm vs. 1.8 ± 1.0 mm, p < .001; 1.7 ± 0.6 mm vs. 1.2 ± 0.3 mm, p < .01). Regarding GI, PD, post-operative pain, aesthetic outcomes, and patient satisfaction, no significant difference could be detected. Moreover, the operation time of XCM group was shorter (60 ± 9 min vs. 39 ± 8 min, p < .001).Conclusions: FGG could result in greater increase of KMW than XCM, though both could increase KMW, maintain peri-implant health, and attain comparable aesthetic outcomes. The use of XCM was associated with reduced operation time.
K E Y W O R D Scollagen matrix, dental implants, free gingival graft, keratinized mucosa, randomized controlled trial
Clinical RelevanceScientific rationale for study: The clinical efficacy of xenogeneic collagen matrix (XCM) for augmenting keratinized mucosa width (KMW) around implants has been documented. However, limited randomized controlled trials have compared the performance of XCM with free gingival grafts (FGG).Principal findings: FGG resulted in greater increase of KMW, though both XCM and FGG could attain >2 mm KMW. The use of XCM was associated with reduced operation time.Practical implications: FGG is a predictable option in augmenting KMW around implants. XCM could be a valid alternative for patients with a certain amount of keratinized tissue surrounding surgical sites at baseline and low acceptance for soft tissue graft harvesting.Jia-Ping Huang and Jia-Mei Liu contributed equally to this study.