The Performance of p-Aminosalicylic Acid As Reducing and Stabilizing Agent in Silver Nanoparticles Synthesis

Abstract

In this study, silver nanoparticles (AgNPs) were successfully synthesized using p-aminosalicylic acid as a reducing and stabilizing agent simultaneously. The AgNPs was synthesized by mixing silver nitrate solution as a precursor with the pH adjusted by p-aminosalicylic acid solution and heating it in a boiling water bath. The formed AgNPs were analyzed using UV-Vis spectrophotometry to evaluate their SPR absorbance in the wavelength range of 400-500 nm. The optimum reaction time is 10 min and the optimum pH is 11. The AgNPs with the optimum synthesis condition have average size of 32.3 nm when characterized using PSA, spherical morphology when characterized using TEM, and face-centered cubic crystal when chara­cterized using XRD. The formed AgNPs had good stability for more than 2 months. The mechanism of silver ion reduction and AgNPs stabilization by p-aminosalicylic acid were also proposed in the paper based on the FTIR analysis result.

Antibacterial Activity of Silver Nanoparticles Synthesized Using Tyrosine as Capping and Reducing Agent

“…Silver nanoparticles were able to store Ag + ions in a longer period of time so that testing with antibacterial, Ag + ions have released and produce inhibitor zones in the bacterial. In previous studies, smaller AgNPs would provide higher antibacterial activity because the smaller AgNPs size has a higher surface area which can increase the site of contact with the bacteria [30]. However, the results of this study are different.…”

Formulation of Mupirocin Adsorbed Silver Nanoparticle with Antibiofilm Agents for Enhancing Antibacterial Activity

“…Particle size of AgNP with PASA as reducing agent has the particle size distribution between 140 nm to 204 nm which was larger than that is reported by Dian susanthy et al synthesized AgNP using PASA 14 even though the pH was 11 and the reaction time 20 min. PDI between 0.3 to 0.5 indicating the homogeneity of the formulation.…”

Синтез Наночастинок Срібла На Основі Алізарину S

“…Відновниками можуть бути різноматні природні та синтетичні сполуки, однак у Web-пошуку не вдається знайти інформацію про використання з цією метою Алізаринового червоного S (Алізарину S, ARS). Як правило, автори подібних досліджень, наприклад [1], постулюють двохелектронний окисно-відновний процес за участю фенольних сполук. Однак, молекули речовин, подібних до Алізарину S, як відновники, можуть надавати значно більшу кількість електронів, і відповідно, трансформуватись через ряд проміжних продуктів окиснення до стану коли їх відновна здатність буде вичерпана.…”