The pentraxin family in autoimmune disease

Li, Yongzhen; Zhang, Shouzan; Liu, Jingqi; Zhang, Yudi; Zhang, Nan; Cheng, Quan; Zhang, Hao; Wu, Xiaochuan

doi:10.1016/j.cca.2023.117592

Cited by 1 publication

(1 citation statement)

References 192 publications

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“…Interestingly, PTX4 is not induced by IL-1 or LPS and does not act as an acute-phase protein. Its high expression has been found in traumatic brain injury (TBI) [54,55].…”

Section: Pentraxin Familymentioning

confidence: 99%

The Role of Pentraxin 3 in Gastrointestinal Cancers

Zajkowska,

Mroczko

2023

Cancers

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Gastrointestinal cancers have become a huge problem worldwide as the number of new cases continues to increase. Due to the growing need to explore new biomarkers and therapeutic targets for the detection and treatment of cancerous lesions, we sought to elucidate the role of Pentraxin-3 in the progression of cancerous lesions, as it is involved in the process of angiogenesis and inflammation. Statistically significant changes in the concentration of this parameter have emerged in many gastrointestinal cancer patients. Moreover, it is related to the advancement of cancer, as well as processes leading to the development of those changes. In the case of studies concerning tissue material, both increased and decreased tissue expression of the tested parameter were observed and were dependent on the type of cancer. In the case of cell lines, both human and animal, a significant increase in Pentraxin 3 gene expression was observed, which confirmed the changes observed at the protein level. In conclusion, it can be assumed that PTX3, both at the level of gene expression and protein concentrations, is highly useful in the detection of gastrointestinal cancers, and its use as a biomarker and/or therapeutic target may be useful in the future.

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“…Interestingly, PTX4 is not induced by IL-1 or LPS and does not act as an acute-phase protein. Its high expression has been found in traumatic brain injury (TBI) [54,55].…”

Section: Pentraxin Familymentioning

confidence: 99%

The Role of Pentraxin 3 in Gastrointestinal Cancers

Zajkowska,

Mroczko

2023

Cancers

View full text Add to dashboard Cite

show abstract

The pentraxin family in autoimmune disease

Cited by 1 publication

References 192 publications

The Role of Pentraxin 3 in Gastrointestinal Cancers

The Role of Pentraxin 3 in Gastrointestinal Cancers

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