“…In the study by Mantziou, Vrellis, Tassos, and Mikropoulus [21] instead, the possibility of recognizing emotions in subjects with autism was investigated, thanks to the use of an avatar, able to recreate facial expressions inherent to specific emotions (anger, fear, happiness, surprise). Further evidence was provided by studying the use of an avatar [22,23] in Attention Deficit/Hyperactivity Disorder (ADHD) [24][25][26][27]. These studies suggest that an avatar can be used as a computerized pedagogical agent with realistic characteristics; for example, it can appear on a computer screen and guide users through multimedia learning environments, designed to support learning and direct attention to relevant topics.…”