The Pattern of Rheumatoid Arthritis in the Indian Population: A Prospective Study

Chopra, Arvind; Raghunath, D; Singh, Arti; Subramanian, Anita

doi:10.1093/rheumatology/27.6.454

Cited by 18 publications

(6 citation statements)

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“…Family history 14% [23] found that out of 110 patients who came for evaluation of polyarthritis 89 had rheumatoid arthritis. Looking at the features of rheumatic disorders in a referral hospital in South India, rheumatoid arthritis was seen in elderly men and age of onset was 37.4 ± 9 years.…”

Section: Rheumatoid Arthritismentioning

confidence: 99%

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Prevalence of arthritis in India and Pakistan: a review

2011

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Recent studies of rheumatoid arthritis worldwide suggest that prevalence of arthritis is higher in Europe and North America than in developing countries. Prevalence data for major arthritis disorders have been compiled in West for several decades, but figures from the third world are just emerging. A coordinated effort by WHO and ILAR (International League Against Rheumatism) has resulted in collecting data for countries like Philippines, China, Malaysia, Indonesia, and rural South Africa but the information about prevalence of arthritis in India and Pakistan is scarce. Since both countries, i.e., India and Pakistan, share some ethnic identity, we reviewed published literature to examine the prevalence of arthritis in these countries. Medline and Pubmed were searched for suitable articles about arthritis from 1980 and onwards. Findings from these articles were reviewed and summarized. The prevalence, clinical features, and laboratory findings of rheumatoid arthritis are compiled for both India and Pakistan. Data collected from these two countries were compared with each other, and some of the characteristics of the disease were compared with Europe and North America. It is found to be quite similar to developed countries. Additionally, juvenile rheumatoid arthritis is of different variety than reported in West. It is more of polyarticular onset type while in West pauciarticular predominates. Additionally, in systemic onset, JRA uveitis and ANA are common finding in developed countries; on the other hand, they are hardly seen in this region. Although the prevalence of arthritis in Pakistan and India is similar to Western countries, there are inherent differences (clinical features, laboratory findings) in the presentation of disease. The major strength of the study is that it is the first to pool reports to provide an estimate of the disease in the Indian subcontinent. Scarcity of data is one of the major limitations. This study helps to understand the pattern of disease in this part of country that can be stepping-stone for policy makers to draft policies that can affect target population more appropriately.

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Section: Rheumatoid Arthritismentioning

confidence: 99%

“…The prevalence of osteoarthritis was 5.8(95% CI: 5.1-6.5) [4]. The prevalence of osteoarthritis was less in 30 years old than between older than 65 years old [23]. The female to male ratio was found to be 1.3:1.…”

Section: Osteoarthritismentioning

confidence: 99%

Prevalence of arthritis in India and Pakistan: a review

2011

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“…Nine studies included data on comorbidities among RA patients (Table a). The comorbidities reported in more than one study included anemia, dyslipidemia and Sjögren's syndrome . The comorbidities reported among 30% or more of total RA patients included anemia, dyslipidemia, leukocytosis, thrombocytosis, tuberculosis and infections of unknown organisms (never isolated) …”

Section: Resultsmentioning

confidence: 99%

“…The percentages of patients diagnosed with extra‐articular manifestations that were not specified ranged from 15% to 61%. The specific extra‐articular manifestations reported among 20% or more of total RA patients included amyloid deposits, anxiety, subclinical atherosclerosis, malaise, neuropathy, osteoporosis and splenomegaly . Additionally, interstitial lung disease, small vessel vasculitis and uveitis were reported among juvenile RA patients…”

Section: Resultsmentioning

confidence: 99%

“…Ten studies reporting comorbidities and/or extra‐articular manifestations among RA patients also provided the RF seropositivity of RA patients; RF seropositivity ranged from 68% to 90% . In only one study of extra‐articular manifestations, the anti‐CCP assay was given to RA patients presenting to a hospital clinic in New Delhi; among 42 RA patients; the seropositivity was 90% …”

Section: Resultsmentioning

confidence: 99%

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Literature review of rheumatoid arthritis in India

Handa

Rao

Lewis³

et al. 2015

Int J Rheum Dis

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Aim: Rheumatoid arthritis (RA) can lead to severe disability. This literature review assessed the descriptive epidemiology, comorbidities and extra-articular manifestations, functioning abilities and quality of life, and treatment patterns of RA patients in India. Method: A literature review of all observational studies published from 1985 to 2012 was conducted using MEDLINE and Embase. Quantitative and qualitative findings were summarized. Results: Twenty-eight studies were identified for data extraction. Seven described the descriptive epidemiology of RA, 14 described comorbidities and extra-articular manifestations, nine described the functioning abilities and quality of life among patients, and 10 provided information on treatments. Conclusion: This review is confined to studies with small sample sizes, cross-sectional designs, and/or clinical settings that may not be representative of the entire Indian population. There is a need for more robust studies, as conclusions for the entire Indian RA population cannot be drawn from only the current observational studies.

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The expression of rheumatoid arthritis in Saudi Arabia

Al-Balla

1995

Clin Rheumatol

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This retrospective study describes the characteristics of rheumatoid arthritis patients seen at the King Khalid University Hospital, Riyadh over a period of 5 years. One hundred and ninety-five patients with rheumatoid arthritis seen during this period were reviewed. There were 155 females and 40 males (F:M ratio 4:1). Females had a younger age at onset than males (38.6 +/- 13.4 vs 42.9 +/- 13.3 year for male - p = 0.037). The majority of patients (76.4%) described an insidious onset. 45.1% used one or more forms of local medicine. Constitutional symptoms were reported in 78 (40%). Rheumatoid factor was positive in 79.5%. The most frequently involved joints were the proximal interphalangeal (PIP) joints, knees and metacarpophalangeal (MCP) joints. Rheumatoid nodules were observed in 15.9% and keratoconjunctivitis sicca in 14.4%. Most patients used second line drugs. The majority of patients (57.4%) were in functional class 1 and 2. The disease pattern and joint distribution resemble more the pattern reported in developed countries.

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The Pattern of Rheumatoid Arthritis in the Indian Population: A Prospective Study

Cited by 18 publications

References 0 publications

Prevalence of arthritis in India and Pakistan: a review

Prevalence of arthritis in India and Pakistan: a review

Literature review of rheumatoid arthritis in India

The expression of rheumatoid arthritis in Saudi Arabia

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