The pattern of childhood malignancy in Eastern Nigeria

Fi, Obioha; Wn, Kaine; Se, Ikerionwu; Go, Obi; To, Ulasi

doi:10.1080/02724936.1989.11748643

Cited by 14 publications

(8 citation statements)

References 8 publications

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“…2,[11][12] As in other studies [1][2][3][4][5][6]14 late presentations with advanced disease compounded by delays in establishing a diagnosis and starting treatment were also problems encountered in management in this study.…”

Section: Discussionmentioning

confidence: 50%

“…[1][2][3][4][5][6][7]12 These numbers are considerably lower however than the number of new cases per year seen in some developed countries. 8,9 The existence of a National cancer registry in those countries helps greatly to kept accurate statistic of the disease burden.…”

Section: Discussionmentioning

confidence: 96%

“…The pattern of childhood cancers in Nigeria has remained largely unchanged over the last 40 years with Burkitts lymphoma being the predominant cancer in Nigerian children 1,3,4,7,12 . This was also shown in this study.…”

Section: Discussionmentioning

confidence: 99%

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Childhood malignancies in University of Abuja Teaching Hospital Gwagwalada, Abuja, Nigeria.

Offiong¹

2012

Nig. J. Paed.

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Abstract:Background: Mortality from malignancies in children remains high. Creating awareness of the disease and advocacy for funding of a cancer research center are pertinent. Objective: To determine the incidence and outcome of children with cancers at the University of Abuja Teaching Hospital, Gwagwaglada, Abuja-FCT, Nigeria Method: This was a 5 year prospective study of all diagnosed cancer patients admitted into the paediatric ward. The type of cancer, method of diagnosis, clinical staging and outcomes were entered and frequency tables generated on Microsoft Excel. Results: Forty-six patients were diagnosed with cancer within the study period. Burkitt's lymphoma was the highest encountred malignancy, while medulloblastoma was least occurring. Only 36.9 percent (N=17) of patients received chemotherapy. Of these, 6.5 percent (n=3) completed therapy. Twenty nine percent of patients died. 4 percent of those that died had commenced chemotherapy. There was a 70 percent treatment default rate. One patient was referred on request to another tertiary center. All other patients were lost to follow up. Conclusion: Management of childhood cancers still poses a problem. Poverty, ignorance and lack of cancer research units contributed to our poor outcome. The greater involvement of government and international non-governmental organizations (NGO) which assist health sector is advocated in the establishment of cancer research centers and the provision of free chemotherapeutic agents.

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Section: Discussionmentioning

confidence: 50%

Section: Discussionmentioning

confidence: 96%

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Childhood malignancies in University of Abuja Teaching Hospital Gwagwalada, Abuja, Nigeria.

Offiong¹

2012

Nig. J. Paed.

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“…[1] The pattern of childhood cancer in America and Europe are almost the same, with leukemia and tumors of the central nervous system accounting for over one-half of the cases. Many papers have been published on pattern of pediatric cancer in some Arab countries, [2][3][4][5][6][7][8][9] However, reports on pattern and incidence of childhood cancer in Saudi Arabia are very few. The objective of this study is to determine the patterns of childhood cancer in Hail Region, Saudi Arabia.…”

Section: Introductionmentioning

confidence: 99%

Pattern and Outcome of Pediatric Leukemia and Lymphoma among Cancer Children Admitted to King Khalid Hospital in Hail Region, Saudi Arabia – Hospital Based Study

Alhabi¹,

Alshammari²,

Alkhateeb³

et al. 2017

AIMDR

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Background: Cancers form one of the major causes of mortality and morbidity in children between the ages of one and 15 years. Childhood cancers are histologically more diverse than adult cancers; they differ in type, distribution, etiology and prognosis from adult cancers. Childhood cancers are more influenced by genetic and environmental factors. The patterns of childhood cancers in America and Europe are almost similar, where leukemia tumors accounting for over one-half of cancer cases. In contrast, lymphoma is the most common prevailing cancer among children in Africa. The objective of this study is to determine the patterns of childhood tumors in Hail region, Saudi Arabia. Methods: This was a retrospective descriptive study conducted in king Khalid hospital, Hail, Kingdom of Saudi Arabia (KSA) during the period from October 2016 to March 2017. A full coverage of data regarding leukemia and lymphoma were retrieved from the hospital. Obtained data were filled in standard form prior to analysis. The study was approved by ethical committee at college of medicine, university of Hail. Data were analyzed using SPSS software version 16. P value < 0.05 was considered statistically significant. Results: The results showed a pattern of childhood leukemia as the most common cancer (60.8%). The prevalence of cancer was found to be higher among males (58.3.7%) than females (41.7%) with a rate of 1.3:1. Most of the children admitted with cancer were from Hail region (63.3%). Majority (41.7%) of cancer children had good prognosis and where discharged home. Conclusion: Hematological malignancies were the most common form of cancer among our patients. The pattern of childhood tumors showed wide variation during the study.

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“…Burkitt's lymphoma is the commonest paediatric malignant tumour seen in various studies in Nigeria [2,3,[7][8][9][10][11][12][13][14][15][16][17][18][19]. Common childhood malignant neoplasms in other parts of the world include intracranial tumours; neuroblastoma, osteosarcoma, Ewing's sarcoma, and soft tissue sarcoma.…”

Section: Introductionmentioning

confidence: 99%

Histopathological Pattern of Childhood Solid Tumours in Ilorin: A 28-Year Retrospective Review

Omotayo¹,

Duduyemi²,

Mo³

et al. 2013

AJMSM

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Background: Cancers and other non-communicable diseases were thought to be unimportant public health problems in developing countries because of the overwhelmingly high prevalence of communicable diseases. However, with improved health care facilities and extensive national immunization programmes, coupled with generally improving socio-economic status, malignant diseases are beginning to account for a significant percentage of childhood morbidity and mortality. The study aims to determine the morphological pattern, burden and demographic characteristics of paediatric solid malignancies seen at the University of Ilorin Teaching Hospital between January 1979 and December 2006. Methodology: The demographic characteristics of all cases of malignant solid neoplasms seen in children between the ages of 0 and 15 years were retrieved from the archives and recorded. The histopathological, cytological and the post-mortem slides of the recorded cases were retrieved and reviewed. Special staining techniques were employed where necessary. Results: Three hundred and twenty four cases of childhood solid malignant neoplasms were diagnosed over the study period. The prevalence of childhood malignant solid tumours in Ilorin is 311 per million children. The commonest tumour in this study is lymphoma representing 55.56% of total paediatric malignant solid neoplasms seen. Burkitt's lymphoma constituted the largest single entity (80% of all lymphomas). This was followed by nephroblastoma, retinoblastoma and bone tumours which accounted for 8.33%, 7.72% and 4.63% respectively. Intracranial tumours were relatively rare. Conclusion: The pattern of paediatric malignant solid neoplasms seen in Ilorin is similar to what obtains in other parts of Nigeria and African countries. Burkitt's Lymphoma is the commonest childhood malignancy in this study. Nephroblastoma is the second commonest childhood malignant solid neoplasm in Ilorin as against what was observed in other centres such as Ibadan, Ife and Jos where retinoblastoma is the second commonest after lymphoma.

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The pattern of childhood malignancy in Eastern Nigeria

Cited by 14 publications

References 8 publications

Childhood malignancies in University of Abuja Teaching Hospital Gwagwalada, Abuja, Nigeria.

Childhood malignancies in University of Abuja Teaching Hospital Gwagwalada, Abuja, Nigeria.

Pattern and Outcome of Pediatric Leukemia and Lymphoma among Cancer Children Admitted to King Khalid Hospital in Hail Region, Saudi Arabia – Hospital Based Study

Histopathological Pattern of Childhood Solid Tumours in Ilorin: A 28-Year Retrospective Review

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