The Pathophysiology and Treatment of Pyoderma Gangrenosum—Current Options and New Perspectives
Magdalena Łyko,
Anna Ryguła,
Michał Kowalski
et al.
Abstract:Pyoderma gangrenosum (PG) is an uncommon inflammatory dermatological disorder characterized by painful ulcers that quickly spread peripherally. The pathophysiology of PG is not fully understood; however, it is most commonly considered a disease in the spectrum of neutrophilic dermatoses. The treatment of PG remains challenging due to the lack of generally accepted therapeutic guidelines. Existing therapeutic methods focus on limiting inflammation through the use of immunosuppressive and immunomodulatory therap… Show more
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