The Pathophysiological Mechanism and Treatment of Secondary Brain Insult of Hypertensive Intracerebral Hemorrhage

Abstract

Hypertensive intracerebral hemorrhage (HICH) is a type of acute cerebrovascular disease with high rates of incidence, mortality, and disability, and is a cause of more frequent instances of secondary brain insult (SBI). In-depth study of the pathogenesis and pathophysiological mechanisms of SBI in HICH contributes to its clinical treatment and prognosis. This article presents a brief summary of the pathophysiological mechanism and treatment of SBI after HICH.

Effect of hyperglycemia at admission on the outcome of surgical evacuation of supratentorial spontaneous intracerebral hemorrhage

“…Pathophysiologically, hyperglycemia is caused by the disruption of blood glucose regulation in the brainstem due to the mass effect of hematoma and brain herniation. 12 Previous studies have shown that the prevalence of hyperglycemia in patients with SICH is 51%. 13 Although a higher cut-off value was used to define hyperglycemia (7.77 mmol/L rather than 6.5 mmol/L), this study showed a higher prevalence of 65%.…”