The Pathology of Foetal Maceration: A Study of 24 Cases

Acta Obstet Gynecol Scand

Samuelsen

Eskild

2013

Both small and large placentas relative to birthweight were associated with fetal death in preterm births. At term, only small placentas relative to birthweight were associated with fetal death. Understanding the mechanisms behind the increased risk of adverse pregnancy outcomes in pregnancies with disproportionate placental weight/birthweight ratio may be important for prevention of fetal deaths.

Section: Discussionmentioning

confidence: 99%

Fetal death and placental weight/birthweight ratio: a population study

Acta Obstet Gynecol Scand

Samuelsen

Eskild

2013

“…152 All these factors could potentially influence placental weight after fetal death, but birthweight may also change due to morphological changes that occur in the fetus after death. Fetal weight may increase as a consequence of tissue oedema, 154 or decrease because of atrophy and autolysis. 155 If the placental weight/birthweight ratio changes as a function of fetal death, our findings may be biased due to differential misclassification.…”

Section: Information Biasmentioning

confidence: 99%

The impact of maternal age on fetal death: does length of gestation matter?

American Journal of Obstetrics and Gynecology

Sarfraz

Samuelsen

et al. 2010

“…The occurrence of fetal death could possibly influence birthweight [17,18]. Nevertheless, it is unlikely that such changes are differential by maternal preeclampsia status, birthweight or year of birth.…”

Section: Discussionmentioning

confidence: 99%

Temporal changes in fetal death risk in pregnancies with preeclampsia: Does offspring birthweight matter? A population study

European Journal of Obstetrics & Gynecology and Reproductiv

Strøm‐Roum

Eskild

2019

Objectives To study the associations of preeclampsia with fetal death risk within percentiles of offspring birthweight, and whether these associations have changed during 1967–2014. Study design In this population study, we included all singleton pregnancies in the Medical Birth Registry of Norway during 1967–2014 (n = 2 607 199). Odds ratios (ORs) for fetal death associated with preeclampsia were estimated within percentiles of birthweight by applying logistic regression analyses. We estimated ORs for the study period as a whole, and for the years 1967–1983 and 1984–2014. Results During the study period as a whole, preeclampsia increased the risk of fetal death, OR 2.73 (95% CI 2.57–2.89), and the fetal death risk associated with preeclampsia differed across percentiles of offspring birthweight. The overall risk of fetal death decreased during our study period, and the decrease was most prominent in preeclamptic pregnancies with low offspring birthweight (<1 percentile). Thus, in recent years, the risk of fetal death in pregnancies with low offspring birthweight was lower in preeclamptic than in non-preeclamptic pregnancies, OR 0.22 (95% CI 0.12-0.41). Only in pregnancies with offspring birthweight within the 10–90 percentiles, the risk of fetal death associated with preeclampsia remained significantly increased throughout the study period. Conclusions The decline in fetal death risk was most prominent in preeclamptic pregnancies with low offspring birthweight. The introduction of a national screening program for preeclampsia in the 1980s, and identification of growth restricted offspring by fetal ultrasonography, may explain our findings.