The Pathology of Fibrotic Lesions

Pugh, R. C. B.

doi:10.1177/003591576005300830

Cited by 26 publications

(7 citation statements)

References 21 publications

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“…In our series, the coexistence of Dupuytren's diathesis with Peyronie's disease was much higher at 47%. The maximum incidence of the disease occurred between the fortieth and sixtieth year and is similar to that reported by Ashworth (1960) and Pugh (1960). There is no difference in this series in the clinical findings which were reviewed by McRoberts (1969).…”

Section: Discussionsupporting

confidence: 87%

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The Non-surgical Treatment of Peyronie's Disease

Williams

Green

1980

British Journal of Urology

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Forty-five patients with Peyronie's disease are described. No patient received treatment for one year from the time of presentation. Three had a complete resolution of their symptoms and signs during this period. The remaining patients received injections of triamcinolone hexacetonide (Lederle) into the plaques at 6-weekly intervals for 36 weeks. Thirty-three per cent had complete or marked improvement in their symptoms; those responding were younger patients with small, firm, discrete plaques in the distal penis. We recommend a non-operative approach in this group. Surgery or chemotherapy should be reserved for those older patients with harder, larger or confluent plaques.

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Section: Discussionsupporting

confidence: 87%

“…A higher proportion of plaques occurred in the distal penis in our patients. In other larger series, an equal incidence has been reported, plaques occurring throughout the length of the penis but not in the glans (Pugh, 1960).…”

Section: Discussionmentioning

confidence: 73%

The Non-surgical Treatment of Peyronie's Disease

Williams

Green

1980

British Journal of Urology

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“…CONNECTIVE TISSUE DISEASE (PUGH, 1960; AND OTHERS) The disease is inflammatory, affects mainly connective tissue, is accompanied by disturbance of plasma proteins and occasionally by arteritis or arthritis of 'rheumatoid' type; it is corticosteroid sensitive. The similarities to the 'connec-tive tissue diseases' are striking, but so far lack confirmation using conventional methods.…”

Section: Toxoplasmosismentioning

confidence: 99%

The pathology of idiopathic retroperitoneal fibrosis

Mitchinson

1970

J Clin Pathol

194

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The salient pathological findings in 40 patients with idiopathic retroperitoneal fibrosis are summarized. The findings tend to confirm previous suggestions that this chronic inflammatory disease is potentially widespread, predominantly peri-aortic, associated with systemic disturbances, and of some fundamental interest. The name `systemic idiopathic fibrosis' is suggested for the disease complex. The study suggests that damage to the wall of the aorta and its large branches might be the cause.

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“…Pugh (1960) draws attention to the differences between localized collagenous deposits and generalized collagen disease. Quoting Barrett (1958), he divides the localized forms into two groups, first Peyronie's disease, Dupuytren's contracture, and keloid scars.…”

Section: Discussionmentioning

confidence: 99%

Combined mediastinal and retroperitoneal fibrosis

Salmon¹

1968

Thorax

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The Pathology of Fibrotic Lesions

Cited by 26 publications

References 21 publications

The Non-surgical Treatment of Peyronie's Disease

The Non-surgical Treatment of Peyronie's Disease

The pathology of idiopathic retroperitoneal fibrosis

Combined mediastinal and retroperitoneal fibrosis

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