The Pathology of Endomyocardial Fibrosis in Uganda

Davies, J. N. P.; Ball, Jonathan

doi:10.1136/hrt.17.3.337

Cited by 198 publications

(62 citation statements)

References 25 publications

(4 reference statements)

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“…4) But there seems little reason to doubt that this patient had endomyocardial fibrosis. The diseases with which it could be confused are endocarditis parietalis fibroplastica (Loffler)27) and cardiovascular collagenosis with mural thrombus (Becker).28) These are, however, easily ruled out by the history, clinical and laboratory findings, and pathological examination.…”

Section: Discussionmentioning

confidence: 99%

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A Case of Diffuse Endomyocardial Fibrosis of the Right Ventricle with Persistent Pericardial Effusion

Ito

Fujino

et al. 1976

Jpn Heart J

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Section: Discussionmentioning

confidence: 99%

“…The protein content of the pericardial fluid was high, always over 3.0Gm%. At last, the pericardiectomy was performed on Feb. 4,1975. However, the patient died after the operation.…”

Section: Case Reportmentioning

confidence: 99%

A Case of Diffuse Endomyocardial Fibrosis of the Right Ventricle with Persistent Pericardial Effusion

Ito

Fujino

et al. 1976

Jpn Heart J

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“…An association with eosinophils in the pathogenesis of endomyocardial fibrosis was already suggested by Davies and Ball (1955). Subsequently, Parry and Abrahams (1965) noted patients in Nigeria, either diagnosed as Loffler's disease or heart muscle disease due to filariasis.…”

Section: Introduction and Pathologymentioning

confidence: 93%

Pathological aspects of endomyocardial fibrosis

Olsen¹

1983

Postgraduate Medical Journal

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Summary The studies leading up to the unitarian concept suggesting that endomyocardial fibrosis, described in the tropics, and Löffler’s endocarditis parietalis fibroplastica (Löffler’s endomyocardial disease), described in the temperate zone, belong to the same disease spectrum are detailed. Evidence that the eosinophil is involved in the pathogenesis of endomyocardial diseases, irrespective of the geographical origin, is presented. The findings of a similar abnormality in these cells obtained from patients in the tropical and temperate zones are briefly mentioned. In view of the evidence it is proposed that endomyocardial disease, associated with abnormal eosinophils, hitherto classified under the restrictive type of cardiomyopathy, be removed from this classification and reclassified under ‘specific heart muscle disease’.

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“…[1,2] Although first described in Uganda, [3] this condition has been documented throughout the world, particularly in tropical and subtropical zones in Africa, Asia and South America. [1,2] Its aetiology remains elusive.…”

mentioning

confidence: 99%

A case of biventricular endomyocardial fibrosis complicated by right ventricular outflow tract aneurysms

Gonçalves

Meel

2016

S Afr Med J

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Endomyocardial fibrosis remains a major public health problem worldwide. It is a restrictive cardiomyopathy, of uncertain aetiology, which may lead to right, left or biventricular heart failure. Progress continues to be made in understanding the prevalence and natural history of this disease. Specific treatment, apart from surgery, remains suboptimal. We report a case of advanced, biventricular EMF complicated by right ventricular outflow tract aneurysms.

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The Pathology of Endomyocardial Fibrosis in Uganda

Cited by 198 publications

References 25 publications

A Case of Diffuse Endomyocardial Fibrosis of the Right Ventricle with Persistent Pericardial Effusion

A Case of Diffuse Endomyocardial Fibrosis of the Right Ventricle with Persistent Pericardial Effusion

Pathological aspects of endomyocardial fibrosis

A case of biventricular endomyocardial fibrosis complicated by right ventricular outflow tract aneurysms

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