“…Prior to antibiotic therapy, septic cavernous sinus thrombosis implied significant morbidity and often death (Dixon, 1926;Grove, 1936;Yarington, 1961). Those who survived were faced with severe neurological and ophthalmological deficit, including cranial nerve abnormalities, visual field loss, decreased visual acuity or blindness, and in rare instances, hemiparesis, hypopituitarism, focal seizures, and vascular steal syndrome (Levine et al, 1988;Southwick et al, 1986).…”