The path to equitable HIV prevention

Idoko, John; Grinsztejn, Beatriz; Phanuphak, Nittaya

doi:10.1038/s43856-022-00224-2

Cited by 1 publication

(1 citation statement)

References 9 publications

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“…Throughout human history, viral infections have persistently threatened our wellbeing. Notably, viruses such as human immunodeficiency virus (HIV), influenza, and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have presented formidable challenges on a global scale [1][2][3]. In their quest for replication and survival, these viruses manipulate and exploit the cellular structures and processes of the host [4].…”

Section: Introductionmentioning

confidence: 99%

Host Subcellular Organelles: Targets of Viral Manipulation

Song,

Lee,

Lee

et al. 2024

IJMS

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Viruses have evolved sophisticated mechanisms to manipulate host cell processes and utilize intracellular organelles to facilitate their replication. These complex interactions between viruses and cellular organelles allow them to hijack the cellular machinery and impair homeostasis. Moreover, viral infection alters the cell membrane’s structure and composition and induces vesicle formation to facilitate intracellular trafficking of viral components. However, the research focus has predominantly been on the immune response elicited by viruses, often overlooking the significant alterations that viruses induce in cellular organelles. Gaining a deeper understanding of these virus-induced cellular changes is crucial for elucidating the full life cycle of viruses and developing potent antiviral therapies. Exploring virus-induced cellular changes could substantially improve our understanding of viral infection mechanisms.

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