The pastoral age in Australasia, by James Collier.

Abstract

Fae away in the South Seas, a hundred years ago, more or less, the humane British Government was engaged in making a social experiment that had an issue undreamt of by its benevolent originators. It sent out to the newly discovered wilds of New South Wales successive contingents of its convicted felons, not only from the natural desire of getting rid of its worst citizens, but also with the hope of reforming criminals who could, by no possible chance, be reformed in England. The design succeeded beyond the hopes of its promoters, but far less through the measures taken by them with that end in view, than as an indirect result of unforeseen occurrences. While its representatives at the Antipodes, the rulers of the new British colony, were planting out so many of its " exiles " on farms near the settlement or employing the more skilled among them in works of public utility, an altogether new development

Haemodynamic and metabolic effects of combined adrenergic α‐ and β‐receptor blockade with labetalol in the exercising human forearm

“…administration of labetalol lowers the resting arterial blood pressure as seen in the present study. This is a consistent finding in healthy subjects [9,181 and in hypertensive patients [8,[19][20][21], and is probably predominantly due to the a-receptor blocking part of labetalol as P-receptor blocking agents do not reduce the resting blood pressure acutely [22, 231. A marked decrease in the blood pressure and giddiness were seen in the upright position, probably elicited by venous pooling of blood due to the a-receptor blockade [24]. Orthostatic faintness after i.v.…”

“…Likewise, in patients on long-term treatment with labetalol, postural faintness is an occasional side effect only (6, 7, 191. Conflicting results have been obtained as to the effect of labetalol on heart rate at rest [8,9,18,20,21], whereas all reports agree that labetalol reduces the heart rate response to exercise, where sympathetic tone is raised [8, 9, 18, 211. In the present study heart rate increased just after the labetalol injection, probably due to the a-receptor blockade [24,251). Later, during forearm exercise and in the recovery phase the fall in heart rate indicated that the P-receptor blockade had prevailed.…”

“…Labetalol has been shown to counteract the effects of noradrenaline and isoprenaline infused intra- arterially in the resting human forearm [9]. However, little is known of its peripheral haemodynamic and metabolic effects when there is no previous stimulation with exogenous catecholamines.…”

Deficient antipneumococcal polysaccharide responses in HIV-seropositive patients

“…No statistically significant correlation between antibody level and opsonic activity was observed (r = 0.096, P = 0.404). [32]. The ability of a host to produce specific antibodies against capsular polysaccharides is constituted by the activation of B cells by crosslinking of surface antigen receptors in the absence of T cells.…”

Development and Characterization of Eco-Friendly Sisal Fiber-Natural Rubber Latex Composites

“…Paul Wambua et al Studied the viability of Natural fibers as a replacement to Synthetic fibers [16]. Collier [17] studied the effect of cotton fibers in rubber. Effect of fiber diameter on mechanics of rubber composites was studied by Zhang et al [18].…”