The Past and Future of Angiogenesis as a Target for Cancer Therapy and Prevention
Adriana Albini,
Douglas M. Noonan,
Paola Corradino
et al.
Abstract:Cancer growth is dependent on angiogenesis, the formation of new blood vessels, which represents a hallmark of cancer. Since this concept was established in the Seventies, inhibition of tumor development and metastases by blocking the neoangiogenic process has been an important approach to the treatment of tumors. However, antiangiogenic therapies are often administered when cancer has already progressed. The key to reducing the cancer burden is prevention. We noticed 20 years ago that a series of possible can… Show more
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