1961
DOI: 10.1042/bj0780827
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The partition of solutes between buffer solutions and solutions containing hyaluronic acid

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Cited by 269 publications
(104 citation statements)
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“…Most of the influx of protein in inflammatory fluids is probably due to an increase in capillary permeability. It is likely, however, that in normal and noninflammatory fluids at least some portion of serum protein is excluded from the articular cavity because of inability to penetrate the domain of the high molecular weight hyaluronic acid (30).…”
Section: Discussionmentioning
confidence: 99%
“…Most of the influx of protein in inflammatory fluids is probably due to an increase in capillary permeability. It is likely, however, that in normal and noninflammatory fluids at least some portion of serum protein is excluded from the articular cavity because of inability to penetrate the domain of the high molecular weight hyaluronic acid (30).…”
Section: Discussionmentioning
confidence: 99%
“…In the present experiments the mannitol space has been measured. Mannitol is likely to give a better estimate than inulin, which is probably hindered by steric barriers in the extracellular space (Ogston & Phelps, 1960;Goodford & Leach, 1966). Table 3 shows the mannitol space in muscles soaked for 1 hr in various media and expressed as ml./g.…”
Section: Sodium In Diaphragm 263mentioning
confidence: 99%
“…The exclusion properties of mucopolysaccharide gels were investigated by Ogston & Phelps (1961) and Laurent (1964). In view of their individual molecular radii, it is not therefore surprising to find that inulin equilibrates within a smaller space than does raffinose which in turn equilibrates within a smaller space than does sucrose (I.S.…”
Section: Saccharide Spaces In the Gastrocnemius 553mentioning
confidence: 99%