The PacELF programme: will mass drug administration be enough?

Burkot, Tom; Ichimori, Kazuyo

doi:10.1016/s1471-4922(01)02221-8

Cited by 60 publications

(65 citation statements)

References 27 publications

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“…26,27 Our findings support this strategy for areas with low-to-moderate rates of transmission in regions where anopheline mosquitoes transmit this infectious disease, such as in Melanesia and Africa. Additional measures or longer periods of treatment may be nec- Our results suggest that mass treatment will be well accepted.…”

Section: Discussionsupporting

confidence: 71%

Mass Treatment to Eliminate Filariasis in Papua New Guinea

et al. 2002

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Section: Discussionsupporting

confidence: 71%

Mass Treatment to Eliminate Filariasis in Papua New Guinea

et al. 2002

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“…The challenges to MDA programs have led to growing concerns regarding the effectiveness of using MDA alone to eliminate LF without the inclusion of vector control (12,13). This is especially pertinent given that vector control was once advocated as the primary tool to control filariasis (66), and the approach was feasible in some epidemiological settings, as demonstrated by the elimination of Anopheles-transmitted filariasis from Solomon Islands (75,77,78) and Togo (9,67) by indoor spraying with dichloro-diphenyltrichloroethane (DDT).…”

Section: Growing Recognition Of the Potential And Need To Include Vecmentioning

confidence: 99%

“…quinquefasciatus is increasing with urbanization and human activity, and many rural pockets that were relatively free of this mosquito are now increasingly colonized (20). (12,14). It breeds in artificial and natural containers of rainwater, such as coconut shells, fallen coconut leaf bracts, discarded tins, old automobile tires, and drums, as well as in tree holes, canoes, and crab holes made in sandy beaches.…”

Section: Culex Speciesmentioning

confidence: 99%

Role of Vector Control in the Global Program to Eliminate Lymphatic Filariasis

Bockarie

Pedersen

White

et al. 2009

Annu. Rev. Entomol.

222

197

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Lymphatic filariasis (LF) is a major cause of acute and chronic morbidity in the tropical and subtropical parts of the world. The availability of safe, single-dose, drug treatment regimens capable of suppressing microfilaremia to very low levels, along with improvements in techniques for diagnosing infection, has resulted in the targeting of this major mosquito-borne disease for global elimination. The Global Program to Eliminate Lymphatic Filariasis (GPELF) was launched in 2000 with the principal objective of breaking the cycles of transmission of Wuchereria bancrofti and Brugia spp. through the application of annual mass drug administrations (MDAs) to entire at-risk populations. Although significant progress in initiating MDA programs in endemic countries has been made, emerging challenges to this approach have raised questions regarding the effectiveness of using MDA alone to eliminate LF without the inclusion of supplementary vector control. Here, we review advances in knowledge of vector ecology, vector-parasite relationships, and both empirical and theoretical evidence regarding vector management to assess the feasibility and strategic value of including vector control in the GPELF initiative to achieve the global elimination of LF.

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“…polynesiensis becomes infected when feeding on low microÞlaremic blood. This efÞciency has been posited as a cause for rebounds in lymphatic Þlariasis prevalence after cessation of previous mass drug administration (MDA) programs, and justiÞes the inclusion of vector control in elimination programs (Burkot and Ichimori 2002). However, this day-active species is difÞcult to control using traditional methods, owing to its tendency to rest and bite outdoors and use of unobtrusive natural and artiÞcial containers as larval development sites.…”

mentioning

confidence: 99%

Determinants of Male <I>Aedes aegypti</I> and <I>Aedes polynesiensis</I> (Diptera: Culicidae) Response to Sound: Efficacy and Considerations for Use of Sound Traps in the Field

2013

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Understanding the mating competitiveness of male mosquitoes in Þeld settings is essential to programs relying on the mass release of modiÞed male mosquitoes, yet studies on male ecology have been hampered by the lack of a convenient trapping method. An existing promising method makes use of the innate attraction of males to female ßight tones. Here, we present laboratory, greenhouse, and Þeld experiments on the efÞcacy of sound traps for the collection of Aedes aegypti (L.) and Aedes polynesiensis Marks, and laboratory experiments with Ae. aegypti on the effects of male age, size, and mating status on responsiveness to a range of frequencies. Age and mating status inßuenced the overall responsiveness to sound, whereas male size did not. There were no interactions between these factors and sound frequency. A Centers for Disease Control and Prevention miniature light trap modiÞed to produce a tone of 465 Hz collected 76.2% of Ae. aegypti males in laboratory cages, and 49.7% of males in a greenhouse enclosure. In two sets of experiments in laboratory cages, 50.8 and 46.5% of male Ae. polynesiensis were captured with a trap producing a tone of 440 Hz. In the Þeld, CDC miniature light traps or BG-Sentinel traps Þtted with a portable speaker producing tones of 440 or 465 Hz captured signiÞcantly more male Ae. polynesiensis when placed near a male swarm than did traps that did not produce sound. When the trap was placed at a distance of 16.5 m from the nearest swarm, there was no signiÞcant difference in the number of males caught between control and sound-producing traps. The numbers of Ae. aegypti males captured were low under all circumstances in the Þeld.

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The PacELF programme: will mass drug administration be enough?

Cited by 60 publications

References 27 publications

Mass Treatment to Eliminate Filariasis in Papua New Guinea

Mass Treatment to Eliminate Filariasis in Papua New Guinea

Role of Vector Control in the Global Program to Eliminate Lymphatic Filariasis

Determinants of Male <I>Aedes aegypti</I> and <I>Aedes polynesiensis</I> (Diptera: Culicidae) Response to Sound: Efficacy and Considerations for Use of Sound Traps in the Field

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