“…For instance, for nanoparticles (NP), the determination of particle size, the dynamics of agglomeration and aggregation, the area, and the charge are mandatory for any toxicological evaluation [22]. In the field of urban particles, considering that they are complex mixtures, there are no standard measurements of physicochemical and chemical components, but the determination of total carbon, black carbon, transitional metals, nitrates, sulfates, oxidative potential, and polycyclic aromatic hydrocarbons is among the most evaluated components [23, 24]. A recent report of a meta-analysis and multisite time series evaluating elemental carbon, organic carbon matter, sulfate, and nitrate on PM 2.5 and in its relation to hospital admissions demonstrates that changes in elemental carbon content are associated with cardiovascular hospital admissions [25].…”